DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7458 and UST4r

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	583	Identity:	145/583 - (24%)
Similarity:	247/583 - (42%)	Gaps:	94/583 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYV-------FTASTVVHRCTVP------QCDSP 92
            :|.::|..||:||:.       |:|..|.|:..|       |||:...|||.||      ..|:.
  Rat     6 LLNQVGGLGRFQILQ-------MVFVVFTSVIVVPHIIIENFTAAIPSHRCWVPILDNVTVSDND 63

  Fly    93 SSVYEED-WLGFTIP-KKNSAWDDCHRYA------ANISDAISGYTDPSGQYCLKEYFTITSETC 149
            |.:..:| .|..:|| ..:...|.|.|:|      .:::|..|..|:|..:.|:.
  Rat    64 SRILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSITEPDTEPCVD---------- 118

  Fly   150 GRDFKFRDEEKTISTEFGIYCEDE-----WKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAV 209
            |..:...:...|..||:.:.||.:     .|||.:     :|.|:|..:.|..:||:||:.:|..
  Rat   119 GWVYDRSNFHSTTVTEWNLVCESQALNSVTKLSFM-----IGAFIGGIVNGLLSDRFGRKFILKY 178

  Fly   210 AGSVSALMGVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAF---LLAIELVGPKRRVAAATIITIF 271
            |....|:.......:.|..::....||   .|.:|.|...   ||..|...||    ..|::|:.
  Rat   179 ALLQMAITETCAGFAPNLFIYCSLRFL---AGMSLEPITVNINLLMFEWTSPK----FLTMVTVL 236

  Fly   272 YALGEAFLGF----LASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRR 332
            .:...:|.|.    ||.|.|:|..|...:..|....::....|.||.|||:.....:|....|::
  Rat   237 GSCAGSFGGMILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQKGLKELKK 301

  Fly   333 AARIN--QRPLPEEQLNDLLTSNRQKLSQANES-------QYPIMRAVVFFSLRIANCCLCWFTH 388
            .|.||  ::......:..:.||.:::|..|...       ..||:|..::         :..|..
  Rat   302 VAHINGMKKSGDNITMEVVRTSMKKELEAAKMRPSPRDLFHTPILRKQIY---------ILSFIR 357

  Fly   389 TLIAL---GLSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLV---IMDRVGRRHSLCASMLLCAIC 447
            .|..|   |::::..:|..|..   :|...|.:..:|..::   :::.:|||.:....|.|..|.
  Rat   358 LLFILSGVGVAIHLQHLSNNIE---LLQILISVSSILFSVIGHFVLNHIGRRITQMVIMFLRGIS 419

  Fly   448 MGASAAVP--ADNYAGSLALFLIGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSML 510
            :..:...|  .:.....:|:...|..|::.:...|:  .:|:.||.:|.|...:..|.|.||..|
  Rat   420 ILTAIFAPQEMETLRFIMAMMAEGLAALSYAANSLH--ANELLPTTLRATARGVIGMFGNIGFFL 482

  Fly   511 APQTPLLAKYYIYAPQILFATFALISGFLTLAFPETADKVLP-TTIEEARDLNQAKRRSERSP 572
            ||...:||.|....|.|.:..||::|||:.|..|||.:..|| .|.:...|..::::..:..|
  Rat   483 APLCMMLASYSPNLPWIFYGGFAILSGFIVLLLPETKNNPLPDCTHDVENDWKESRQEMKEDP 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	141/558 (25%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	102/411 (25%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	106/442 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347320
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940