Protein Alignment CG7458 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 450
• Identity: 119/450 - (26%)
• Similarity: 182/450 - (40%)
• Gaps: 76/450 - (16%)

  Fly   162 ISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSN 226
            :|..:.:.|.|.||:.:....:.:|..:|..:.|...||:|||.:...:..::..:|...:|:::
Human     5 LSQNWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAAS 69

  Fly   227 YSMFLVFEFLDMAVGSTL---FPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQH 288
            :...||...|.   |.||   ....:|..:||..|..|:|.:....:|..:|...|..||:.||.
Human    70 FPTLLVLRLLH---GGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALVQD 131

  Fly   289 WRWLLRVLYAPAVLQILFLW----ILPESVRWLLSQGAEEKASNVLRRAARIN-----QRPLPEE 344
            || ||:.|.|.....:|..|    :.|||..|||:.|...:|..:|.|.|..:     ...|.|.
Human   132 WR-LLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEEN 195

  Fly   345 QLNDLLTSNRQKLSQAN-ESQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNL-GGNKY 407
            .|...||....:..|.. .|...::|..|           .|..      ||.|...:| ||...
Human   196 SLATELTMLSARSPQPRYHSPLGLLRTRV-----------TWRN------GLILGFSSLVGGGIR 243

  Fly   408 TNFMLNGFIQIPGLLLP---------------LVIMDRVGRRHSL--------CASMLLCAICMG 449
            .:|..:...|:|...||               |:..|..|||..|        .||:||.|
Human   244 ASFRRSLAPQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLA---- 304

  Fly   450 ASAAVPADNYAGSLALFL--IGKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAP 512
                 .|....|...|||  :|.||......:...|.:|:|||.:|...|.|....|.:|....|
Human   305 -----GAQYLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGP 364

  Fly   513 QTPLLAKYYIYAPQILFATFALISGFLTLAFPETADKVLPTTIEEARDLNQAKRRSERSP 572
            ...|..:...:..|::||:.|:::....|..||:..:.||.::::|       .|..|||
Human   365 LDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDA-------DRLRRSP 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	114/430 (27%)
		MFS	161..544	CDD:119392	110/420 (26%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	106/403 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010