Protein Alignment CG7458 and SLC22A7

DIOPT Version :9

• Sequence 1: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_011512558.1
• Gene: SLC22A7 / 10864
• HGNCID: 10971
• Length: 610
• Species: Homo sapiens
• Alignment Length: 608
• Identity: 158/608 - (25%)
• Similarity: 264/608 - (43%)
• Gaps: 112/608 - (18%)

  Fly    39 DAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEED-WLG 102
            :.:|.::|.||.:|:.|..||.:|.:......:..:|.|:...|||.:|  .:|::...:| ||.
Human     4 EELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALP--GAPANFSHQDVWLE 66

  Fly   103 FTIPKK-NSAWDDCHRYAANISDAISGYT-------------DPSGQYCLKEYFTITSETCGRDF 153
            ..:|:: :.....|.|:|  ...|:...|             :|:...|.:          |.::
Human    67 AHLPREPDGTLSSCLRFA--YPQALPNTTLGEERQSRGELEDEPATVPCSQ----------GWEY 119

  Fly   154 KFRDEEKTISTE--FGIY-------C-------------------------------EDEWKLSM 178
            ...:...||:||  .|||       |                               ...|:.|:
Human   120 DHSEFSSTIATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSWRESL 184

  Fly   179 VGTINNV---------------------GQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRS 222
            .|.::.:                     |..||....||.:||:|||.:|.||...:.::|:..:
Human   185 GGLLSGMEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASA 249

  Fly   223 LSSNYSMFLVFEFLDMAVGSTLFPTAFLL------AIELVGPKRRVAAATIITIFYALGEAFLGF 281
            .|.:|.||.:...|   .||.|.....::      .:|.:..:.|..|..:.:.|:..|...|..
Human   250 ASVSYVMFAITRTL---TGSALAGFTIIVMPLGEAELEWLDVEHRTVAGVLSSTFWTGGVMLLAL 311

  Fly   282 LASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQL 346
            :...::.|||||..:..|....||.||.:|||.||||:||..::|...|...||:|.||:.|:..
Human   312 VGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSF 376

  Fly   347 NDLLTSNRQKLSQANESQYPIMRAV---VFFSLRIANCCLC----WFTHTLIALGLSLNSVNLGG 404
                  :::.:|:....:..:.|..   :|.:.|:.:..||    ||.......||||:...||.
Human   377 ------SQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGL 435

  Fly   405 NKYTNFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIG 469
            |.|...:|.|.:::|..||..:.:...|||.:...::|..|:..|....|.:|..:.|..|.::|
Human   436 NVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMG 500

  Fly   470 KLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFAL 534
            |.....:|...|.||||::||.:|.|.:.|.::|||:|..|||...||...::..|::.:...||
Human   501 KAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIAL 565

  Fly   535 ISGFLTLAFPETADKVLPTTIEE 557
            ::....|..|||....||.||::
Human   566 LAAGTALLLPETRQAQLPETIQD 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	155/596 (26%)
		MFS	161..544	CDD:119392	123/456 (27%)
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	155/596 (26%)
		MFS	206..563	CDD:119392	109/365 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020