DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7458 and slc22a13

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_031760340.1	Gene:	slc22a13 / 100491580	XenbaseID:	XB-GENE-959647	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	571	Identity:	157/571 - (27%)
Similarity:	260/571 - (45%)	Gaps:	77/571 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDS------PSSVYEED 99
            ||..:|:|||:|....|:|.:....|||...|.||....|.||     |||      ..::.|.:
Frog     7 ILKNVGEFGRFQKQLVVVLSLLSFLNAFHMFSQVFMEIPVPHR-----CDSRWILLINPNLTEAE 66

  Fly   100 WLGFTIPKKNSAWDDCHRYAANISDAISGYTDPSGQY--CLK-----------EYFTITSE-TC- 149
            .|.:|||:                       |..|||  ||.           |.|.:.|. .|
Frog    67 RLNYTIPR-----------------------DGRGQYEQCLMYSPVQWDMESIEKFGLNSTGPCQ 108

  Fly   150 -GRDFKFRDEEKTISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSV 213
             |.::...:::.|:.|:|.:.|....:..:..::...|..:|..|.|...||.|||.::.::..:
Frog   109 DGWEYDTSEQKSTLVTQFDLVCHRREQTGISQSVYMSGLLIGALLFGPLGDRIGRRPVILLSMLL 173

  Fly   214 SALMGVIRSLSSNYSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAF 278
            ..:.|:..:.:.::.::..|.::.....|.|.....:|..|.||..||..|.....:.:|:|...
Frog   174 QLVFGLSAAFAPHFYVYTAFRWVVGTSMSGLMINNLVLGAEWVGSSRRACATITAHVCFAVGLMA 238

  Fly   279 LGFLASQVQHWRWLLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPE 343
            |..::..:::||.|..|..||..|...::|:||||.||||::|.:|||..:|::||.:|::.:||
Frog   239 LAGVSYGIRNWRLLQIVSSAPTALLFFYIWVLPESARWLLTKGKKEKAVKLLKKAAAMNKKEIPE 303

  Fly   344 EQLNDLLTSNRQKLSQANESQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGNKYT 408
                |||....::.|..:.:...:.|......|.:. .||.||.::|:..|||||..:.|.:.|.
Frog   304 ----DLLFQFNEEKSPKSGNMIDLFRNKTLRKLTLV-MCLVWFVNSLVYYGLSLNVGSFGLDIYL 363

  Fly   409 NFMLNGFIQIPGLLLPLVIMDRVGRRHSLCASMLLC-----AICMGASAAVPADNYAGSLALFLI 468
            ..::.|.::||..:..:..:...||:    .|.:.|     .:|: ...|:|.:.......|.:|
Frog   364 TQLVFGAVEIPARIGAMFAVQLFGRK----PSQMFCLFLGGTVCL-IITAIPRNLPIAITILAVI 423

  Fly   469 GKLAITCSFQILYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFA 533
            ||.:|..||.|.|.:.:|:|||.:|...:.|.||..|:..:.||...||.||:...|..::.:..
Frog   424 GKFSIASSFSICYIYAAEVFPTVIRQNGVGLASMAARVAGITAPLISLLDKYHAAIPMAIYGSGP 488

  Fly   534 LISGFLTLAFPETADKVL------------PTTIEEARDLNQAKRRSERSP 572
            :|.|.|....|||.:|.|            ..|:...|.:|....:.||.|
Frog   489 IIGGILCFLLPETRNKDLQDHTQQDEPIKSSNTLPGERLINGVDHKPERDP 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	149/546 (27%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	109/387 (28%)
slc22a13	XP_031760340.1	2A0119	12..509	CDD:273328	149/534 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020