DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7458 and slc22a20p.1

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_004913725.1	Gene:	slc22a20p.1 / 100489586	XenbaseID:	XB-GENE-6463910	Length:	572	Species:	Xenopus tropicalis

Alignment Length:	536	Identity:	152/536 - (28%)
Similarity:	252/536 - (47%)	Gaps:	27/536 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSPSSVYEEDWLGFTI 105
            :|:.:|..||:|||:..:|.:||||....:....|:|:...|||.||..|:.:..|::|.|...|
Frog     6 LLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFLQNFSAAVPAHRCWVPSLDNNTMGYDQDHLPAFI 70

  Fly   106 PKKNSAWD-DCHRYAANISDAISGYTDPSGQYCLKEYFTITSETC--GRDFKFRDEEKTISTEFG 167
            |...|... .|.||...:....:..|.           |..:|.|  |..:...|...||.||:.
Frog    71 PMDESEKPLSCLRYRKALHSMWTNGTS-----------TNHTEPCEDGWVYDKSDFSSTIVTEWD 124

  Fly   168 IYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSNYSMFLV 232
            :.|:......:..:|...|..||..|.|..:||.|||.:|..:..|.|:.|...:...|:..:..
Frog   125 LVCKLRKMRQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIGSNLVMAVCGTCAAFLPNFITYCT 189

  Fly   233 FEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQHWRWLLRVLY 297
            |..|.....|.:......|.:|...||.|....|:....:..|:..|..||..::.||||...:.
Frog   190 FRCLCGIAFSGITLNTNSLILEWTPPKGRTIMGTLFAAGFTCGQILLAALAYGIREWRWLQFAVS 254

  Fly   298 APAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLND-LLTSNRQKLSQAN 361
            ||.....|:.|::|||.|||:.:|...:|...|:|.|.||.:....::|:: :|.|:.|  |:.|
Frog   255 APFYFFFLYSWLVPESARWLILKGRSHEALKALQRVAIINGKREEGQKLSEMILISHMQ--SELN 317

  Fly   362 ESQYPIMRAVVFFS--LRIANCCL--CWFTHTLIALGLSLNSVNLGGNKYTNFMLN---GFIQIP 419
            :.:.|.....:|.:  :|....||  .||:..:...||.::..|.|   .:.|:|.   |.|.:|
Frog   318 QVKRPHSLFDLFRTPGMRKVTICLMMVWFSSGVAFYGLGMDLQNFG---ISIFLLQFTFGAIDMP 379

  Fly   420 GLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCSFQILYFFT 484
            ..::..::|..:|||.:....::|..:.:..:|.:|.......:.|.:.||..:..||...|.|:
Frog   380 AKVVAALLMTYMGRRVTQATVLILSGVALLTNAFIPQGMKILRMVLAVFGKGCMAASFACAYLFS 444

  Fly   485 SEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFPETADK 549
            .|:|||.:|.|.:.:.:|:.|:||::||...||.:.....|..::...|:|:|.......||.::
Frog   445 GELFPTVIRQTGMGVVAMMARVGSVVAPLVLLLWEISPILPSAIYGIAAIIAGGAATFLMETNNQ 509

  Fly   550 VLPTTIEEARDLNQAK 565
            .||.::||....:|.|
Frog   510 QLPESVEEVEARSQGK 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	147/518 (28%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	109/390 (28%)
slc22a20p.1	XP_004913725.1	MFS	101..485	CDD:391944	109/388 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010