DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7458 and zmp:0000001102

DIOPT Version :9

Sequence 1:	NP_649374.1	Gene:	CG7458 / 40441	FlyBaseID:	FBgn0037144	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_001340340.6	Gene:	zmp:0000001102 / 100000058	ZFINID:	ZDB-GENE-140106-62	Length:	560	Species:	Danio rerio

Alignment Length:	539	Identity:	134/539 - (24%)
Similarity:	246/539 - (45%)	Gaps:	31/539 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 DAILVRIGQFGRYQIINYVLLCVPMLFNAFFSISYVFTASTVVHRCTVPQCDSP--SSVYEEDWL 101
            |.||.....||||||...:||.:|.:......:...|.|:...|.|.:...|:.  .::.:::.|
Zfish    14 DNILDETDGFGRYQIALVMLLFIPRITIPCHFLLNNFIAAIPSHHCDISSLDADGLGNLTQKERL 78

  Fly   102 GFTIP-KKNSAWDDCHRYAANISDAISGYTDPSGQYCLKEYFT--ITSETCGRDFKFRDEE--KT 161
            ..::| :::.....||.:|           .|..|..:....:  :....|...:.|.:..  .|
Zfish    79 IVSVPAQEDGTPASCHMFA-----------HPQFQLLINSSSSSALPVVECQNGWHFDNSTFIST 132

  Fly   162 ISTEFGIYCEDEWKLSMVGTINNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMGVIRSLSSN 226
            ::|:|.:.|:.........||..||...|....|...|:||||:||.|:...|.:..|..:.||:
Zfish   133 LATQFDLVCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSVTSAFSSS 197

  Fly   227 YSMFLVFEFLDMAVGSTLFPTAFLLAIELVGPKRRVAAATIITIFYALGEAFLGFLASQVQHWRW 291
            |.||..|.||.....:.:...:.:|:||.|..|.|.......::.:::|...|...|..|..||.
Zfish   198 YIMFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTFMGLFGSMSWSIGNMLLAGFAFMVTDWRL 262

  Fly   292 LLRVLYAPAVLQILFLWILPESVRWLLSQGAEEKASNVLRRAARINQR-----PLPEEQLNDLLT 351
            |:.::.||..|.....|.:|:|.|||::.|..|.|...|.:.|..|:|     .:..|.|:.::|
Zfish   263 LIVIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNKRLDFTSRVKPETLSTVVT 327

  Fly   352 SNRQ--KLSQANESQYPIMRAVVFFSLRIANCCLCWFTHTLIALGLSLNSVNLGGNKYTNFMLNG 414
            .:.:  ..:..:..:.|.:|.:..|:      .:.|:.......|:|||....|.:.|....:..
Zfish   328 VDHRGHSYTYLDLVKTPQLRKLTLFT------GIVWYGVASTYYGISLNITGFGLDPYLTHFIYA 386

  Fly   415 FIQIPGLLLPLVIMDRVGRRHSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCSFQI 479
            .|::|..:|....:::||||::...:::|...|:..:...|.:.:.....:.::||.....||..
Zfish   387 AIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILINIITPTEYWTFRTVIAVLGKGLSEASFTT 451

  Fly   480 LYFFTSEIFPTNVRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFP 544
            :..:|:|::||.:|...|...:.:.|:|:.::|...||...:...|:::|.:.|:..|.:.|..|
Zfish   452 VILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWKLLPEVIFCSMAIFCGIIALLLP 516

  Fly   545 ETADKVLPTTIEEARDLNQ 563
            ||.:..||.|:|:..|:.:
Zfish   517 ETNNASLPETVEDIEDMRK 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	128/521 (25%)
CG7458	NP_649374.1	MFS	161..544	CDD:119392	100/389 (26%)
zmp:0000001102	XP_001340340.6	Sugar_tr	22..526	CDD:331684	128/520 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000