DRSC/TRiP Functional Genomics Resources

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Protein Alignment PolH and dinB

DIOPT Version :10

Sequence 1:NP_649371.2 Gene:PolH / 40438 FlyBaseID:FBgn0037141 Length:885 Species:Drosophila melanogaster
Sequence 2:NP_414766.1 Gene:dinB / 944922 ECOCYCID:G6115 Length:351 Species:Escherichia coli


Alignment Length:444 Identity:118/444 - (26%)
Similarity:182/444 - (40%) Gaps:123/444 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 RVVLLVDMDCFFCQVEEKQHPEYRNRPLAVVQYNPWRGG-----GIIA-VNYAARAKGVTRHMRG 74
            |.::.|||||||..||.:.:|..|:.|:|:       ||     |:|: .||.||..||...|..
E. coli     2 RKIIHVDMDCFFAAVEMRDNPALRDIPIAI-------GGSRERRGVISTANYPARKFGVRSAMPT 59

  Fly    75 DEAKDLCPEIVLCQVPNIREKADTSKYRDAGKEVANVLQRFTQLLERASVDEAYLDITETVN-HR 138
            ..|..|||.:.|  :|.   :.|.  |::|...:..:..|:|..:|..|:||||||:|::|: | 
E. coli    60 GMALKLCPHLTL--LPG---RFDA--YKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCH- 116

  Fly   139 MQQMQSGAFALQPQELVNTFAVGYPSIGDYVNKITNRFANPYMDDERYQMSYDQNDLPAVRQSDI 203
                  |:..|                                                      
E. coli   117 ------GSATL------------------------------------------------------ 121

  Fly   204 RLLIGASVAGEVRAAVKKETGYECSAGIAHNKILAKLAAGMNKPNKQTILPLTETASLFDSLPVG 268
                   :|.|:|..:..|.....|||:|..|.|||:|:.|||||.|.::...|..:...:||:.
E. coli   122 -------IAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLA 179

  Fly   269 KIKGLGGKFGEVVCETLGIKFMGQVVKFSEVDLQRKFDEKNGTWLFNISRGIDLEAVTPRFYSKS 333
            ||.|: ||......|.:|::..|.|.|...|.|.::|. |.|..|:..|:|||...|......||
E. coli   180 KIPGV-GKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFG-KFGRILWERSQGIDERDVNSERLRKS 242

  Fly   334 IGCCKKFPGRNNITGLKTLQHWLGELSSEINDRLEKDFIENNRRAKHMVVQYVQDIDGEEVASSR 398
            :|..:        |..:.:.||     ||....:|:.:.|..||        :..:..:.:.:.:
E. coli   243 VGVER--------TMAEDIHHW-----SECEAIIERLYPELERR--------LAKVKPDLLIARQ 286

  Fly   399 STALRDYD-----QESI-VRLS-LDLIKANTKTFLRPGSESALNNAIKFLGISV 445
            ...|:..|     ||.: .||: .|||....||:    .|......::.:|:.|
E. coli   287 GVKLKFDDFQQTTQEHVWPRLNKADLIATARKTW----DERRGGRGVRLVGLHV 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PolHNP_649371.2 PolY_Pol_eta 20..447 CDD:176456 117/440 (27%)
zf_UBZ 705..736 CDD:465769
zf_UBZ 805..832 CDD:465769
dinBNP_414766.1 PRK02406 9..351 CDD:235035 115/437 (26%)
Blue background indicates that the domain is not in the aligned region.

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