Protein Alignment DNApol-eta and RAD30

DIOPT Version :9

• Sequence 1: NP_649371.2
• Gene: DNApol-eta / 40438
• FlyBaseID: FBgn0037141
• Length: 885
• Species: Drosophila melanogaster
• Sequence 2: NP_010707.3
• Gene: RAD30 / 852028
• SGDID: S000002827
• Length: 632
• Species: Saccharomyces cerevisiae
• Alignment Length: 676
• Identity: 153/676 - (22%)
• Similarity: 256/676 - (37%)
• Gaps: 187/676 - (27%)

  Fly    21 VDMDCFFCQVEEKQHPEYRNRPLAVVQYNPWRGGGIIAVNYAARAKGVTRHMRGDEAKDLCPEIV 85
            :||:.||.|||:.:....:..|:..||:|     .||||:||||..|::|.....||...|..::
Yeast    29 IDMNAFFAQVEQMRCGLSKEDPVVCVQWN-----SIIAVSYAARKYGISRMDTIQEALKKCSNLI 88

  Fly    86 L------------------C---------QVPNIREKADTSKYRDAGKEVANVLQRFTQLLERAS 123
            .                  |         |:.....|.....||...::...:.:....|:||||
Yeast    89 PIHTAVFKKGEDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALKIFKSACDLVERAS 153

  Fly   124 VDEAYLDITETVNHRMQQMQSGAFALQPQELVNTFAV-GYPSIGDYVNKITNRFANPYMDDERYQ 187
            :||.:||:             |..........|.:.: |...:.|.::.|...|...
Yeast   154 IDEVFLDL-------------GRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGG-------- 197

  Fly   188 MSYDQND-LPAVRQ-----------------------SDIRLLIGASVAGEVRAAVKKETGYECS 228
             :||.|. ||.:.:                       .|:.|.:|:.|...:|.::|...||..|
Yeast   198 -NYDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKGIRDSIKDILGYTTS 261

  Fly   229 AGIAHNKILAKLAAGMNKPNKQTILPLTETASLFDSLPVGKIK-----GLGGKFGEVVCETL--- 285
            .|::..|.:.|||:...||:.|||:   :...|.|.|..||.:     .|||..|:.:.:.|
Yeast   262 CGLSSTKNVCKLASNYKKPDAQTIV---KNDCLLDFLDCGKFEITSFWTLGGVLGKELIDVLDLP 323

  Fly   286 ---GIKFM--------GQVVKF--------------SEVDLQRKFD--EKNGTWLFNISRGIDLE 323
               .||.:        ||:.:|              |.:|..:..|  ||    ||.:|||....
Yeast   324 HENSIKHIRETWPDNAGQLKEFLDAKVKQSDYDRSTSNIDPLKTADLAEK----LFKLSRGRYGL 384

  Fly   324 AVTPRFYSKSIGCCKKFPGR--NNITG-LKTLQHWLGELSSEINDRLEKDFIENNRRAKHMVVQY 385
            .::.|...||:...|...|:  |:|.. :..|:.:..||:|.|.| ||:::   |:......|..
Yeast   385 PLSSRPVVKSMMSNKNLRGKSCNSIVDCISWLEVFCAELTSRIQD-LEQEY---NKIVIPRTVSI 445

  Fly   386 VQDIDGEEV-ASSRSTALR--DYDQESIVRLSL----DL-IKANTKTFLRPGSESALNNAIKFLG 442
            .......|| ..|...|.:  ::....::::.:    || ||...|::.          .:..|.
Yeast   446 SLKTKSYEVYRKSGPVAYKGINFQSHELLKVGIKFVTDLDIKGKNKSYY----------PLTKLS 500

  Fly   443 ISVGKFETVSSGQNKLQEMFANQAAKKRRVSGDEPGQ----------LPKVEMEKKQKQTDEFKM 497
            :::..|:.:.. |..:.:||.||....:..:|.|..:          .||:|..|.|....:.|.
Yeast   501 MTITNFDIIDL-QKTVVDMFGNQVHTFKSSAGKEDEEKTTSSKADEKTPKLECCKYQVTFTDQKA 564

  Fly   498 KSFFANYLQGAKKEDAKADGISANPLAAAAGAPNKNFVEEYKHKLHAAVRTEGTVLTSTPAEFKE 562
            ....|:|....|    .::|::    .|...:.|.:|.|:   :|..:.:...:..|:||
Yeast   565 LQEHADYHLALK----LSEGLN----GAEESSKNLSFGEK---RLLFSRKRPNSQHTATP----- 613

  Fly   563 SFFSQYLKQQKKTGQQGSVTSREDSL 588
                     |||     .|||.::.|
Yeast   614 ---------QKK-----QVTSSKNIL 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-eta	NP_649371.2	PolY_Pol_eta	20..447	CDD:176456	120/523 (23%)
		zf_UBZ	705..736	CDD:408236
		zf_UBZ	805..832	CDD:408236
RAD30	NP_010707.3	PolY_Pol_eta	27..505	CDD:176456	120/523 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346022
Domainoid	1	1.000	61	1.000	Domainoid score	I2519
eggNOG	1	0.900	-	-		E1_COG0389
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I1390
Isobase	1	0.950	-	0	Normalized mean entropy	S4070
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001835
OrthoInspector	1	1.000	-	-		otm46657
orthoMCL	1	0.900	-	-		OOG6_102732
Panther	1	1.100	-	-	LDO	PTHR45873
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4551
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.770