DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DNApol-eta and ECO1

DIOPT Version :9

Sequence 1:	NP_649371.2	Gene:	DNApol-eta / 40438	FlyBaseID:	FBgn0037141	Length:	885	Species:	Drosophila melanogaster
Sequence 2:	NP_116683.1	Gene:	ECO1 / 850584	SGDID:	S000001923	Length:	281	Species:	Saccharomyces cerevisiae

Alignment Length:	165	Identity:	33/165 - (20%)
Similarity:	66/165 - (40%)	Gaps:	22/165 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   465 QAAKKRRVSGDEPGQL-PKVEMEKKQKQTDEFKMKSFFANYLQGAKKEDAKADGISANPLAAAAG 528
            :|.|.:|.:|.:|..: .|:::....|.....|......:|...:.::.|..:......|.....
Yeast     2 KARKSQRKAGSKPNLIQSKLQVNNGSKSNKIVKCDKCEMSYSSTSIEDRAIHEKYHTLQLHGRKW 66

  Fly   529 APNKNFVEEYKHKLHAAV----RTEGTV--LTSTPAEFKESFFSQ------YLKQQKKTGQQGSV 581
            :||...: .|..:.|:..    |:.||:  |.|:|.:......:.      |::..|..|:..::
Yeast    67 SPNWGSI-VYTERNHSRTVHLSRSTGTITPLNSSPLKKSSPSITHQEEKIVYVRPDKSNGEVRAM 130

  Fly   582 TSREDSLDVQELA-EELDAIEADNSKDFEEDTEEE 615
            |      ::..|. .||:| ..|.:..:...|||:
Yeast   131 T------EIMTLVNNELNA-PHDENVIWNSTTEEK 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-eta	NP_649371.2	PolY_Pol_eta	20..447	CDD:176456
		zf_UBZ	705..736	CDD:408236
		zf_UBZ	805..832	CDD:408236
ECO1	NP_116683.1	zf-C2H2_3	18..57	CDD:404719	5/38 (13%)
ECO1	NP_116683.1	Acetyltransf_13	209..267	CDD:404721
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4551
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030