Protein Alignment SLC22A and OCT2

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_178054.1
• Gene: OCT2 / 844274
• AraportID: AT1G79360
• Length: 527
• Species: Arabidopsis thaliana
• Alignment Length: 592
• Identity: 144/592 - (24%)
• Similarity: 241/592 - (40%)
• Gaps: 118/592 - (19%)

  Fly     9 ADPAVEVAPPAKDSEDVTL-DAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHR 72
            |:|...:...:..|...:| |.|..::|.||..|.:...|:....:|.|..:...|||.:..|..
plant     2 AEPTQPLLTDSNSSSPRSLDDTIESYIGSFGWAQFLQAALVSFSGVFDAQQTFISVFTDSEPTWH 66

  Fly    73 C--SVEECDLPGSNY-YEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEAC 134
            |  |...|....||. ..|.|.||                     |::|
plant    67 CTDSNSICHESISNICILPKTAWS---------------------WDYS---------------- 94

  Fly   135 AHNEFVFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFV----AD-RYGRSFSIA 194
                     ..|::.:::|:.|..    |.|..:.....|.|..|||.|    || ..||...:.
plant    95 ---------PHVSVISEWGLQCAG----SFVKGLPESSFFVGCLIGGLVLSTLADSSLGRKNMLF 146

  Fly   195 LGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVF-Y 258
            |..::.|:..::..|||:...:.|..|::....:|:.:...|:..||||.|.|. ...:::.| :
plant   147 LSCLVMAISTMLTVFSPNIWVYAVLRFVNGFGRATIGTCALVLSTELVGKKWRG-RVGIMSFFGF 210

  Fly   259 AVGEVLLAMSA--KAFHDWRILLRITYGPSLI--LLAYFWILPESVRWLLSQGKEERAKNILRRA 319
            .:|.:.|.:.|  .....||||...|..|::|  :|..|::. ||.|||..:|:.|.|.:||:|.
plant   211 MLGFLSLPLMAYMNRGSSWRILYAWTSIPTIIYCVLVRFFVC-ESPRWLFVRGRREEAISILKRV 274

  Fly   320 AHVNKRELPES-----VLDKLVLANRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHV---L 376
            |.:...::...     ....|.....::...::.:.|...:.....:|.:...|....:..   |
plant   275 ASIPSTDVSSGGAISMSFSSLPFEEDEEKPSTNVNIFTTMKVLVEKRWALKRLSAVMAIAFGIGL 339

  Fly   377 VYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFT- 440
            ||||:.|.:..||.:.|.:.|:.||:::|...:.|.::|:..||.:|.|.....|:..: .||.
plant   340 VYYGMPLALSNLDFNIYLSAAFNALMDLPANLITLFLVDKLSRRNALIGFTALGGVSSV-LIFAL 403

  Fly   441 --------GADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLA 497
                    ||    |||.|.|:...:..::|.:...:..|::||.:|||.::           :|
plant   404 HNMRIGNHGA----LQLALELISYFSACSAFNMEMIYTIELFPTCVRNSAIA-----------MA 453

  Fly   498 PQTPLLAKYYANAPAMLFAGA----------AIVSGLLTLF---FPETTNVVLPTTVQEADAIGV 549
            .|..:|...:  :|.|:.||.          .:..|||.||   .|||....|..|:.|.:.
plant   454 RQALVLGGVF--SPIMVAAGRKNAFWSFGLFGLAIGLLGLFAVGLPETRGSDLCDTMDEEEC--- 513

  Fly   550 KKQSKSK 556
             |..:||
plant   514 -KDRRSK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	107/433 (25%)
OCT2	NP_178054.1	MFS_OCT_plant	79..497	CDD:340936	115/487 (24%)