Protein Alignment SLC22A and OCT1

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_565059.2
• Gene: OCT1 / 843656
• AraportID: AT1G73220
• Length: 539
• Species: Arabidopsis thaliana
• Alignment Length: 571
• Identity: 139/571 - (24%)
• Similarity: 242/571 - (42%)
• Gaps: 117/571 - (20%)

  Fly    25 VTLDAIL-KHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHR-----CSVEECDLPG- 82
            :|:|.:: :|:|..|..|::..||:.:..:|.|..::..:|:.|....|     ..||...|.|
plant    43 LTVDEVIEQHIGALGFAQILHALLVSIAWIFDAQTTLISIFSDAQPAARLLATGAIVEGASLCGL 107

  Fly    83 -SNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDDEV 146
             |..:|    |..||           :::.:.:||
plant   108 ASGEWE----WIGPK-----------SDTVVSEWN------------------------------ 127

  Fly   147 TISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADR-YGRSFSIALGGILGAVLGVIRSFS 210
                   :.|..::.:::..|:..:|..||..:.|::||. :||..::.|..:|..|.....|||
plant   128 -------LICQHKFLVAVPSTLFFIGSLFGSGVYGYLADSWFGRKKTLLLSCVLTFVTAFAISFS 185

  Fly   211 PSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAF--- 272
            |:...:....|.:....|.:.|.|.|:..|:||.|.|.........|:.:|  .|::...|:
plant   186 PNVWVYAFLRFANGFFRSGIGSCCIVLATEIVGKKWRGQVGQYGFFFFTLG--FLSLPLMAYLER 248

  Fly   273 HDWRILLRIT------YGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPE-- 329
            ..||.|.||.      |...|:..||     ||.||||.:|:.:.|..:|::.|.:|.::||.
plant   249 KSWRNLYRIISFLPLGYAVCLLPFAY-----ESPRWLLVKGRNKEAMVVLKKLARLNGKQLPADL 308

  Fly   330 SVLDKLVLANRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHVL--------VYYGLSLNVV 386
            |::|.  :..||....|||.       |...||.:..     |:.|:        ||||:.||..
plant   309 SLVDP--IPERDDQTSSSEK-------FWKTKWAVKR-----IIMVMMAGFGSGFVYYGIQLNAE 359

  Fly   387 LLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPV----- 446
            .|:.:.|...|..||:|.|..|:...::....||.........:|..|:........:.:
plant   360 NLNFNLYLTVAVNALMEFPAVFIGSFLLGVMNRRPLFSNSSYLAGFACLLCAVLSIHRVIRAISV 424

  Fly   447 ---LQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYA 508
               |||.:..||.:..:.::.|||.:..|::|||:||:.:|........|:..||....|.:..|
plant   425 AKWLQLAVEAVGFMASSTAYDVLYVYCVELFPTNVRNTAVSLLRQAFMLGASAAPLLVALGRESA 489

  Fly   509 NAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKDLD 559
            ....::|..|:::||:::|:..||.|..|..|:.:        |.|:::::
plant   490 MMSFIVFGVASVLSGIVSLWLRETRNAPLYETLAQ--------QGKAEEIE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	108/421 (26%)
OCT1	NP_565059.2	MFS_OCT_plant	102..511	CDD:340936	117/481 (24%)