Protein Alignment SLC22A and OCT6

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_173087.1
• Gene: OCT6 / 838207
• AraportID: AT1G16370
• Length: 521
• Species: Arabidopsis thaliana
• Alignment Length: 586
• Identity: 134/586 - (22%)
• Similarity: 232/586 - (39%)
• Gaps: 127/586 - (21%)

  Fly     9 ADPAVE--VAPPAKDS--------EDVTLDAILKH-LGQFGRFQLIIFLLICLPMMFHAMFSVTY 62
            |||..|  ::....||        |.:|.|.|::. |..||.:|.....|:.|.::|.|......
plant     2 ADPISEPLLSHLTDDSGVNEKTRLEALTFDKIVEQSLSDFGFWQFFQISLVGLALLFDAQQIFIT 66

  Fly    63 VFTAATVTHRC---------SVEECDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHS 118
            |:|.|..|..|         :.:.|.||.|.:     .|.....||
plant    67 VYTDAYPTWHCLNHTICDPSASDICKLPRSAW-----EWDGGSQGK------------------- 107

  Fly   119 VDICSADHFTKNKEACAHNEFVFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFV 183
                                        ::.::||:.|..    |::..:.:...:.|..:|||.
plant   108 ----------------------------SVISEFGLECSS----SLLRGMPSSAFYIGAIVGGFF 140

  Fly   184 A-----DRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVG 243
            .     |..||...:.......::..:...||.:...:...:|:...:.|..:|...|:..|.|.
plant   141 LALIPDDSLGRKKLVLFSTFAMSITSISVIFSTNVWIYTFLKFIIGFSRSQTWSYALVLISERVS 205

  Fly   244 PKRRVLACSVITVFYAVGEVLLAMSAKAF----HDWRILLRITYGPSLILLAYFWILP-ESVRWL 303
            .:.|..|..:....:.:|  .:::|..||    ..||.|...|..|::....:.::.. ||.|||
plant   206 TRWRPRATMIPFTLFVLG--FMSLSGIAFLAQDSSWRYLYLYTSVPAVFYCIFLYLFALESPRWL 268

  Fly   304 LSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQQSSESRFPIREAFKNFKWRIANCS 368
            ..|||::.|.::|.:.:...|..| |||:.||.| .::..:|:  ..:.|::.|.. ||......
plant   269 HMQGKDKEAIDVLTKMSPKEKAYL-ESVVSKLPL-KQENFEQA--PTYSIKDFFFR-KWAFRRIL 328

  Fly   369 LCWIVHV---LVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLAS 430
            :..|:..   :.|||:.|....:|.:.|.:....||||:|.|.:..::::||.||.|:
plant   329 VVMIIMFGLGISYYGVPLAARDIDVNIYLSETLNALVELPTFVITPILLERFNRRSSV------- 386

  Fly   431 GLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFAS------------EIYPTNLRNSLL 483
               .:.|:..|| ..||..||.::||..|..:|::..||.:            |::||.:|:|
plant   387 ---LVNTLLGGA-SGVLCFVLSILGKTEIAFAFELGTFFCARIGFNLMAVFMVEMFPTCVRSS-- 445

  Fly   484 SFCSMMGR----FGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEA 544
              .:||.|    .|....|....:.:|..:....:|..|....|:..|..|||..:.|..:::|.
plant   446 --ATMMFRQALVVGGACCPLIASIGRYIPSVSFAIFGIAMSGLGMFVLILPETKGLSLCDSMEEQ 508

  Fly   545 D 545
            :
plant   509 E 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	99/422 (23%)
OCT6	NP_173087.1	MFS_OCT_plant	88..494	CDD:340936	106/483 (22%)
		xylE	<220..>314	CDD:182225	28/99 (28%)