DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SLC22A and PHT1;2

DIOPT Version :9

Sequence 1:	NP_649370.1	Gene:	SLC22A / 40437	FlyBaseID:	FBgn0037140	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_001190462.1	Gene:	PHT1;2 / 834355	AraportID:	AT5G43370	Length:	524	Species:	Arabidopsis thaliana

Alignment Length:	494	Identity:	98/494 - (19%)
Similarity:	172/494 - (34%)	Gaps:	161/494 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 LSMVGTINNLGQFFGIPIGGFVADRYGRS------------FSIALGGILG-AVLGVIRSFSPSY 213
            :::.||::  ||.|    .|::.|:.||.            .|:|.|...| ...||:.:.....
plant    76 VALCGTLS--GQLF----FGWLGDKLGRKKVYGLTLIMMILCSVASGLSFGNEAKGVMTTLCFFR 134

  Fly   214 GWF-------------LVFEFLDNMTSSTLYSTCFV---IGIELVGPKRRVLACSVITVF----- 257
            .|.             ::.|:.:..|.....:..|.   :||...|    .:|.:|.::|
plant   135 FWLGFGIGGDYPLSATIMSEYANKKTRGAFIAAVFAMQGVGILAGG----FVALAVSSIFDKKFP 195

  Fly   258 ---YAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFW--ILPESVRWLLSQGKEERAKNILR 317
               |||... |:...:..:.|||:  :.:|.....|.|:|  .:||:.|:....     ||||.:
plant   196 APTYAVNRA-LSTPPQVDYIWRII--VMFGALPAALTYYWRMKMPETARYTALV-----AKNIKQ 252

  Fly   318 RAAHVNK-----RELPESVLDKLVLANRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHVLV 377
            ..|.::|     .||.|.|.|.:      |..:.:...|. :|..:.....:...:..|.:..:.
plant   253 ATADMSKVLQTDIELEERVEDDV------KDPRQNYGLFS-KEFLRRHGLHLLGTTSTWFLLDIA 310

  Fly   378 YYGLSLNVVLLDGDKYNNFAY----------------------IALVE-IPGFFMPLLIMDRFGR 419
            :|..:    |...|.::...:                      |||.. :||::..:..:|..||
plant   311 FYSQN----LFQKDIFSAIGWIPKAATMNATHEVFRIARAQTLIALCSTVPGYWFTVAFIDTIGR 371

  Fly   420 -RYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLV-----------GKLTITASFQVLYFFA-- 470
             :..|.|..:.       |:|           :|.:           .::.....:.:.:|||
plant   372 FKIQLNGFFMM-------TVF-----------MFAIAFPYNHWIKPENRIGFVVMYSLTFFFANF 418

  Fly   471 ----------SEIYPTNLRNSLLSFC-----------SMMGRFGSMLAPQTPLLAKYYANAP--- 511
                      :||:|..||    |.|           :::|.||.:.|.|....||..|..|
plant   419 GPNATTFIVPAEIFPARLR----STCHGISAAAGKAGAIIGAFGFLYAAQNQDKAKVDAGYPPGI 479

  Fly   512 ----AMLFAGAAIVSGLL-TLFFPETTNVVLPTTVQEAD 545
                :::..|.....|:| |...||.....|.....||:
plant   480 GVKNSLIVLGVLNFIGMLFTFLVPEPKGKSLEELSGEAE 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	96/487 (20%)
SLC22A	NP_649370.1	MFS	146..530	CDD:119392	93/477 (19%)
PHT1;2	NP_001190462.1	2A0109	11..516	CDD:129965	96/490 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D762280at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010