DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SLC22A and PHT1;5

DIOPT Version :9

Sequence 1:	NP_649370.1	Gene:	SLC22A / 40437	FlyBaseID:	FBgn0037140	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_180842.1	Gene:	PHT1;5 / 817844	AraportID:	AT2G32830	Length:	542	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	101/508 - (19%)
Similarity:	180/508 - (35%)	Gaps:	151/508 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 LSMVGTINNLGQFFGIPIGGFVADRYGRS--FSIALGGILGAVLGVIRSFSPSYG---------- 214
            ::..||:  .||.|    .|::.|:.||.  :.|.|..::...||...||..|..
plant    76 VAFCGTL--AGQLF----FGWLGDKLGRKKVYGITLMLMVLCSLGSGLSFGHSANGVMATLCFFR 134

  Fly   215 -WF-------------LVFEFLDNMTSSTLYSTCFVI---GIELVGPKRRVLACSVITVFYA--- 259
             |.             ::.|:.:..|.....:..|.:   ||...|....:::.:....|.|
plant   135 FWLGFGIGGDYPLSATIMSEYANKKTRGAFIAAVFAMQGFGILAGGIVSLIVSSTFDHAFKAPTY 199

  Fly   260 ----VGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFW--ILPESVRWLLSQGKEERAKNILRR 318
                ||..:    .:|.:.|||:|  .:|....||.|:|  .:||:.|:....     |:|..:.
plant   200 EVDPVGSTV----PQADYVWRIVL--MFGAIPALLTYYWRMKMPETARYTALV-----ARNTKQA 253

  Fly   319 AAHVNKRELPESVLDKLVLANRDKLQQSSESRFP-------IREAFKNFKWRIANCSLCWIVHVL 376
            |:.::|      ||...::| .::.|.:|.|..|       .||..:.....:...:..|.:..:
plant   254 ASDMSK------VLQVDLIA-EEEAQSNSNSSNPNFTFGLFTREFARRHGLHLLGTTTTWFLLDI 311

  Fly   377 VYYGLSLNVVLLDGDKYNNFAYIALVE-----------------------IPGFFMPLLIMDRFG 418
            .||..:    |...|.|....:|...|                       :||::..:..:|..|
plant   312 AYYSSN----LFQKDIYTAIGWIPAAETMNAIHEVFTVSKAQTLIALCGTVPGYWFTVAFIDILG 372

  Fly   419 RRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLV-----------GKLTITASFQVLYFFA-- 470
            |.:          :..:|.||       :.:.:|.:           .::.....:.:..|||
plant   373 RFF----------IQLMGFIF-------MTIFMFALAIPYDHWRHRENRIGFLIMYSLTMFFANF 420

  Fly   471 ----------SEIYPTNLRNSL--LSFCS-----MMGRFGSMLAPQTPLLAKYYANAPAMLFAGA 518
                      :||:|..||::.  :|..|     ::|.||.:.|.|:....|..|..|    .|.
plant   421 GPNATTFVVPAEIFPARLRSTCHGISAASGKAGAIVGAFGFLYAAQSSDSEKTDAGYP----PGI 481

  Fly   519 AIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKDL----DLVVTATQA 567
            .:.:.||.|.......:|....|.|:....:::.|:..:.    |.||..|.|
plant   482 GVRNSLLMLACVNFLGIVFTLLVPESKGKSLEEISREDEEQSGGDTVVEMTVA 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	93/475 (20%)
SLC22A	NP_649370.1	MFS	146..530	CDD:119392	92/465 (20%)
PHT1;5	NP_180842.1	2A0109	11..518	CDD:129965	96/490 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D762280at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010