Protein Alignment SLC22A and svopa

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_005165254.1
• Gene: svopa / 559162
• ZFINID: ZDB-GENE-060526-336
• Length: 549
• Species: Danio rerio
• Alignment Length: 579
• Identity: 139/579 - (24%)
• Similarity: 213/579 - (36%)
• Gaps: 184/579 - (31%)

  Fly    14 EVAPPAKDS---EDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSV 75
            |.|.|..|:   || .::||     .||.||..:.:|..|..|..||..:.....|..:
Zfish    59 EFANPTDDTFMVED-AVEAI-----GFGTFQWKLSILTGLSWMADAMEMMILSILAPQL------ 111

  Fly    76 EECDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFV 140
                         |..|::|
Zfish   112 -------------HCEWALP--------------------------------------------- 118

  Fly   141 FRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGV 205
                              .|:::::.::..:|......:.|.::|:|||...:.:..:.....|:
Zfish   119 ------------------SWEVALLTSVVFIGMMISSSLWGNISDKYGRKTGLKMSVLWTLFYGI 165

  Fly   206 IRSFSPSYGWFLVFEFLDNM------TSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVG--- 261
            :.:|:|.|||.|....|...      .|.|||:       |.:..:.|.....:|.:|:|:|
Zfish   166 LSAFAPIYGWILFLRALVGFGIGGAPQSVTLYA-------EFLPMRSRATCILLIEIFWALGTVF 223

  Fly   262 EVLLAMSAKAFHDWRILLRITYGPSLILLAY--FWILPESVRWLLSQGKEERAKNILRRAAHVNK 324
            |||||:.......||.||.::..| |.:.|:  || ||||.|:.:..|.:|:|.|.|:|.|..|.
Zfish   224 EVLLAILVMPTLGWRWLLALSTIP-LFIFAFLCFW-LPESARYDVLTGNQEKALNTLKRIAAENN 286

  Fly   325 RELPESVLDKLVLANRDKLQQSSESRFPIREAFK-NFKWRIANCSLCWIVHVLVYYGL------- 381
            ..:|   |.||::|.:       |.|..|::.|. :|:|........|..:...|||:
Zfish   287 VPMP---LGKLIVARQ-------EDRGKIQDLFSPHFRWTTVLLWFIWFSNAFSYYGVVLLTTEL 341

  Fly   382 -------------------SLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRR------- 420
                               ||....|:.|.|.:..:..|.|.||..:.|..:||.|||
Zfish   342 FQEGGVCGGAKGSKMEPGCSLECKYLNSDDYKDLLWTTLSEFPGLLVTLWAIDRLGRRKTMALCF 406

  Fly   421 --YSLCGLMLASGLCCIG-TIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSL 482
              :|||.:.|.|   |:| |..|         |...:.:..|...||..|.:..|:|||..|...
Zfish   407 FVFSLCIVPLYS---CVGRTSLT---------VFIFIARAFIAGGFQAAYVYTPEVYPTATRALG 459

  Fly   483 LSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAG--------AAIVSGLLTLFFPETT 533
            |...|.|.|.|:::   ||.:|:....:...|...        |||.|..|.:   |||
Zfish   460 LGTSSGMARVGALI---TPFVAQVMLESSVYLTLSVYCCCCLLAAIASCALPI---ETT 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	115/449 (26%)
svopa	XP_005165254.1	MFS_SVOP	87..508	CDD:340999	123/536 (23%)