Protein Alignment SLC22A and slc22a13b

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_017209322.1
• Gene: slc22a13b / 556601
• ZFINID: ZDB-GENE-061013-532
• Length: 549
• Species: Danio rerio
• Alignment Length: 512
• Identity: 160/512 - (31%)
• Similarity: 250/512 - (48%)
• Gaps: 16/512 - (3%)

  Fly    30 ILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNY-YEPHTNWS 93
            ||..:|:||.||..:.:.:|||.:|.|......||||.:..|.|:.........|. .|...|.:
Zfish     7 ILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTEEKQLNLT 71

  Fly    94 IPKNGK-DLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFR--DDEVTISNDFGIF 155
            :|.:.| ..:||..:|..|:       ||...:|:..|......:.:|::  .|..|:..:|.:.
Zfish    72 VPLDSKGQYESCKMFTPVEM-------DIEDIEHYGINTTTSCIDGWVYKAPKDSSTLITEFDLV 129

  Fly   156 CDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFE 220
            |:::.......:|...|...|..:.|.:||:|||.|:..|...|..:.||..:|||:...::...
Zfish   130 CENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSLFLQFLSGVGVAFSPNIYVYIALR 194

  Fly   221 FLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRITYGP 285
            |:...|.|.:....||:|.|..|..:|.|...:...|:|:|.:||:..|....:||:|..:...|
Zfish   195 FVVGTTISGISINTFVLGTEWCGSAKRALFTILSHCFFAIGLMLLSGVAYGIRNWRVLQLVLSAP 259

  Fly   286 SLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQQSSESR 350
            ..:...|:||||||.||||:|||.:.||..:.:||.:|.|::.|::|||:...|..|   ||...
Zfish   260 VGLFFIYYWILPESARWLLTQGKLDSAKREILKAARINGRKVSENLLDKMEAENTAK---SSTMI 321

  Fly   351 FPIREAFKNFKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMD 415
            ...|..:.. |..:..|.: |.|..|||||:||||.....|.|.......:.|.|.......::.
Zfish   322 DLFRVGYLR-KRALIMCYM-WFVTSLVYYGVSLNVGNFGLDIYLTQLIFGMAEFPARLSCFPLIQ 384

  Fly   416 RFGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRN 480
            |||||.....::|..|..|:......|..|::..|:.::||.::.|||.::|.:.:|:|||.:|.
Zfish   385 RFGRRICQSVVLLLGGTACLIIPAIPAKYPIVVTVIAVIGKFSLAASFSIVYVYTAELYPTVVRQ 449

  Fly   481 SLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVL 537
            :.:...||..|...:|||...||..|:...|.:::.....|.|.||...|||.|..|
Zfish   450 NGVGLNSMCARVAGILAPLIGLLDVYHHAIPMIIYGSLPFVGGALTFLLPETLNTDL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	124/395 (31%)
slc22a13b	XP_017209322.1	MFS_OAT	100..499	CDD:340932	125/403 (31%)
		xylE	<232..>327	CDD:182225	38/97 (39%)