Protein Alignment SLC22A and Orct2

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 167/551 - (30%)
• Similarity: 279/551 - (50%)
• Gaps: 46/551 - (8%)

  Fly    28 DAILKHLGQFGRFQLIIFLLICL---PMMFHAMFSVTYVFTAATVTHRCSVEECDLP---GSNYY 86
            |..:.|||.|||:|.||:.||||   |:.||.:..   ||..|....||:     ||   ||:|.
  Fly     4 DEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAG---VFLLAKPDFRCA-----LPFENGSSYD 60

  Fly    87 EPHTNW--SIPKNGK----DLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDDE 145
            .|...|  |.|:|.:    |:|....|.|..:|:.::....||:..:.::|         :.:..
  Fly    61 LPTHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSK---------YLNSA 116

  Fly   146 VTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFS 210
            ||   ::.:.|..::..:...::..||...|..:.|.::|:|||...:....::..:.||:...:
  Fly   117 VT---EWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVA 178

  Fly   211 PSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDW 275
            |.|..:.....:...|:|.::...:|:.:|:|||.:|:.|...:.:|::||.:|.|:.|...|||
  Fly   179 PEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDW 243

  Fly   276 RILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANR 340
            |.|......|.||.:.|:||:|||.||||.:|:::.|...:::||..||.|:.:..|.:| |...
  Fly   244 RWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSEL-LDEG 307

  Fly   341 DKLQQSSESRFPIRE-------------AFKNFKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDK 392
            :..::.::.:...:|             .:.|.:.:.....|.|:|...||||||.|...|.|:.
  Fly   308 ENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNV 372

  Fly   393 YNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKL 457
            ..||.....||||.:...||.::|:|||..|||.::.:||..:.|:........|.:...::|||
  Fly   373 LLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKL 437

  Fly   458 TITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVS 522
            .||||:..:|.|::|.:||.:||..|...||:.|...|:||....||..:...|.::.....:|:
  Fly   438 AITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVA 502

  Fly   523 GLLTLFFPETTNVVLPTTVQEADAIGVKKQS 553
            |||:|..|||.|..:..|:.:.:..|.|.::
  Fly   503 GLLSLLLPETHNKPMLETIADGERFGKKTKA 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	120/406 (30%)
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	161/529 (30%)