DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC22A and CG7084

DIOPT Version :9

Sequence 1:NP_649370.1 Gene:SLC22A / 40437 FlyBaseID:FBgn0037140 Length:568 Species:Drosophila melanogaster
Sequence 2:NP_001247235.2 Gene:CG7084 / 42606 FlyBaseID:FBgn0038938 Length:597 Species:Drosophila melanogaster


Alignment Length:579 Identity:148/579 - (25%)
Similarity:251/579 - (43%) Gaps:96/579 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 DSE-DVTLDAILKHLGQFGRFQLIIFLLICLPMMFH-AMFSVTYVFTAATVTHRCSVEECDLPGS 83
            ||| :....|:::..|..||:|.:...:....:.|. ||..:..:.......|.|:|     || 
  Fly    27 DSEFNDPFQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIPDHWCTV-----PG- 85

  Fly    84 NYYEPHTNWS--------IPKNGKDLDSCNR--YTNSELPQWNHS-VDICSA--DHFTKNKEACA 135
               ..:||:|        :||..   |:..|  ::|.|:.|.|.| :...||  .:.||..||| 
  Fly    86 ---RENTNFSLEEWRDITLPKQA---DNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTEAC- 143

  Fly   136 HNEFVFRDD--EVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALG-- 196
            .|.:.:...  |.||..|....|..:..::.|..:..:.:..|..|.|.:.|.|||.|...:.  
  Fly   144 QNGWSYDKTWYESTIPTDHNWVCAKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVV 208

  Fly   197 ----GILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVF 257
                |.||:::     .:.||.|||:...:..:|.::|:.:..:||:|:...:.|    |.|..|
  Fly   209 FCSLGRLGSIM-----CTSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDR----SRIAFF 264

  Fly   258 ----YAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRR 318
                :::|..|:.:.......|...:.:|..|:.::|.:...:.||.|||:|:.:...|...|::
  Fly   265 QSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQK 329

  Fly   319 AAHVN-------KRELPESVLDKLVLANRDKLQQSSESRFPIREAFKNFKWRIAN----CSLCWI 372
            .|.:|       ::||.|       :.:|||    .:..:.|...|..  ||:|.    ....|.
  Fly   330 IAKINGHRFDMTEKELAE-------IYSRDK----QDVTYGIASLFAG--WRLARNTTIMGFSWC 381

  Fly   373 VHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGT 437
            |..:.|:.|.|....:.|:.:.||.|.::||||.:.:...:.|.:|||::.....|.|.:.|:..
  Fly   382 VVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPI 446

  Fly   438 IFTGADQPVLQLVLFLVGKLTITASFQVLYFF-----ASEIYPTNLRNSLLSFCSMMGRFGSMLA 497
            |....|:....|:::|.   |.......|.||     ..|||||.:|.:.::       .|::||
  Fly   447 IVYSTDERYENLMIYLA---TFIKFLNALTFFTVNLQCLEIYPTCMRQTGVA-------LGTILA 501

  Fly   498 PQTPLLAKYYA--------NAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIG 548
            ....:||.|..        .||..:.....::.|:..||.|||.:..||.|::||...|
  Fly   502 NAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFG 560

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC22ANP_649370.1 2A0119 35..540 CDD:273328 140/554 (25%)
MFS 146..530 CDD:119392 102/417 (24%)
CG7084NP_001247235.2 2A0119 64..552 CDD:273328 135/532 (25%)
MFS 184..542 CDD:119392 97/389 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 100 1.000 Domainoid score I351
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 97 1.000 Inparanoid score I321
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000012
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24064
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
55.060

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