Protein Alignment SLC22A and CG4462

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_650849.1
• Gene: CG4462 / 42376
• FlyBaseID: FBgn0038752
• Length: 573
• Species: Drosophila melanogaster
• Alignment Length: 586
• Identity: 126/586 - (21%)
• Similarity: 225/586 - (38%)
• Gaps: 99/586 - (16%)

  Fly    10 DPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCS 74
            |..:...|||....||..|.:    |.||.:||...|:|.|..:..|.|....:||...:
  Fly    27 DKRIATPPPAPAGSDVIADVV----GDFGIWQLRTILIIFLCKIPAAWFMACIIFTGPEL----- 82

  Fly    75 VEECDLPGSNYYEPHTNWSIPKNGKDLDSCNR--YTNSELPQWNHSVDICSA-DHFTKNKEACAH 136
                 .|||.:                 :|:.  .|:|....::.|.:.|.. |..|.....|..
  Fly    83 -----YPGSEF-----------------TCDTSYLTSSSNSSFSISDNQCYVLDESTGTSSECEQ 125

  Fly   137 NEFVFRDDEVTISNDFGIFC--------DDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFS- 192
            ..:|...|.:.:  .|.:.|        ...|.|            ||:.:||.:..:.....|
  Fly   126 FNYVSSFDSLIM--QFNLVCLRDIFVAWTQYWHL------------FGVLVGGVMGTKMMLGISP 176

  Fly   193 ---IALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVI 254
               ..:|.:...:.||:..::..:.....|..|..:..:.:::....|..::.....|:.|..:.
  Fly   177 RSTYCVGAVAQILCGVVTGYARDFSLHCAFRCLSAVCCAIMFTAGQAIFADITAGMHRIGAIILY 241

  Fly   255 TVFYAVGEVLLAMSAKAFHDWRIL-LRITYGPSLILLAYFWILPESVRWLLSQGKE----ERAKN 314
            ..|:::|.:||...:..|:.|.:: :.||:...:::|..:| .|:|.||||....:    :..:.
  Fly   242 DTFWSIGVILLPGLSSFFNSWSLIYVGITFPTIMLILLLYW-TPDSPRWLLRHAADRFSIDNVEQ 305

  Fly   315 ILRRAAHVNKRELPESVLDKLVLANRDKLQQSSE------SRFPIREAF--KNFKWRIANCSLCW 371
            |||..|.:|.|..      |:....|.:|:|.||      ...|..|.:  |..|..:....|..
  Fly   306 ILREGAAINDRSF------KIPPDFRQQLEQLSERLKAQPPPAPWTELWKGKRAKTHMVAAHLAL 364

  Fly   372 IVHVLVYYGLSLNVVLLDGDKY--NNFAYIALVEIPGFFMPLLIMDRFGR-RYSLCGL--MLASG 431
            ...|:.:.|:.||:.....|..  |..| :...||.|.|:.|....:..: ::...|:  :||..
  Fly   365 AFFVINFMGMLLNIRSFGRDYLVPNTIA-MGFSEIIGCFLALHFTLKHNKWKWQCAGVFNILAGI 428

  Fly   432 LCCIGTIFTGAD------QPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMG 490
            |.|:|.|||.||      :..|.:::..:.|..::.:..::....:|:.|.|.:...:.......
  Fly   429 LGCMGWIFTNADSMDADLKVSLWMIIATIPKAAVSCAQSMILACMNELMPANKKQLFVFSVVTWA 493

  Fly   491 RFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLT--LFFPE-TTNVVLPTTVQEADAIGVKKQ 552
            |...:.||...:|.|.........:...:|:.|:.|  |..|. :.:.|:|...|.    ..|:|
  Fly   494 RVWLLSAPFFNVLRKIDTAMSLTSYCVFSILGGICTSLLLTPRLSVSPVVPHLEQR----NTKEQ 554

  Fly   553 S 553
            |
  Fly   555 S 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	115/546 (21%)
		MFS	146..530	CDD:119392	87/421 (21%)
CG4462	NP_650849.1	2A0119	<126..532	CDD:273328	88/427 (21%)
		MFS	149..>284	CDD:119392	25/147 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458331
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940