Protein Alignment SLC22A and CG7342

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001247196.1
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 534
• Identity: 123/534 - (23%)
• Similarity: 233/534 - (43%)
• Gaps: 48/534 - (8%)

  Fly    27 LDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYEPHTN 91
            :|.||:..|.|.|.|:|:.||.|:..:..|:...:....:....:.|:   ..||.| ...|..:
  Fly     4 VDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCA---DGLPAS-IESPVDS 64

  Fly    92 WSIP--KNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDDEVTISNDFGI 154
            ..:|  :|....::|..| |.||                    ...:..|....|.|
  Fly    65 SCLPLNRNISTPNTCYSY-NYEL--------------------YMGYQSFPSEMDWV-------- 100

  Fly   155 FCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVF 219
             |.|.|||::..::..:|...|..:.|::||..||...:.:..::.....::..:|.:...|.:|
  Fly   101 -CADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMF 164

  Fly   220 EFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSV-ITVFYAVGEVLLAMSAKAFHDWRILLRITY 283
            ..:..:.:.:.:...:::.:|.:.|..|.|..|: |..||.:|.:.....|.....||..|..|.
  Fly   165 RMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTS 229

  Fly   284 GPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQQSSE 348
            .|.|::..::.|:|||::||:|:.|.:.|...|:|.|.:|.|.:.||...:.:  ...|..|.::
  Fly   230 LPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFI--EECKCSQQNQ 292

  Fly   349 SRFP-IREAFKNFKWRIANCSLCW--IVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMP 410
            ...| :.:.|:..:.|.....|.:  :|..|.|..:|.||..|....:..|:..|...:|...:.
  Fly   293 KASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLI 357

  Fly   411 LLIMDRFGRRYSLCGLMLASGLCCI---GTIF--TGADQPVLQLV-LFLVGKLTITASFQVLYFF 469
            :.:.||.||:......:|.||:...   |.||  :.:|:....|| |.:||:..:|.::.....:
  Fly   358 IALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQY 422

  Fly   470 ASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTN 534
            |:|:.||.:|...::...:.|...:..:.........::..|.::....:::...|.|..|||.:
  Fly   423 ATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLH 487

  Fly   535 VVLPTTVQEADAIG 548
            ..|||::::.:..|
  Fly   488 RTLPTSLEDGENFG 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	118/516 (23%)
		MFS	146..530	CDD:119392	90/393 (23%)
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	116/514 (23%)
		MFS	93..>243	CDD:119392	35/158 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458503
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.990