Protein Alignment SLC22A and CG12783

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001262644.2
• Gene: CG12783 / 42019
• FlyBaseID: FBgn0038448
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 500
• Identity: 101/500 - (20%)
• Similarity: 174/500 - (34%)
• Gaps: 154/500 - (30%)

  Fly   146 VTISNDFGI-------FCDDEWKLSMVGTINNLGQFFGIPIG----GFVADRYGRSFSIALGGIL 199
            :||....|:       .||.....:.:.::...| |.||...    |::.|:.||.:::.....:
  Fly    30 LTIQETMGMGIIGPAAVCDLRMNEAQLASLTAAG-FMGIICSSYFWGYITDKKGRRWTLLRTITI 93

  Fly   200 GAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTC-FVIGIELVGP-------KRRVLACSVITV 256
            ..:..:...|:.::..|.|..|:          || ||.|...|..       ..|::..|:..:
  Fly    94 SNLCSLASMFTVTFTGFFVMRFI----------TCIFVAGPSFVAATYLSEFCSHRIMVRSITHL 148

  Fly   257 FYAVGEVLLAMSAKA--------------------FHDWRILLRITYGPSLILLAYFWILPESVR 301
            :...|..:::..|.|                    ...||:|..:...|.::......:||||.:
  Fly   149 YMFTGFAMISCPAWATLFLSSGLIEFEEKLVGSLTLRPWRVLGCLYILPGVVAFLLLLLLPESPK 213

  Fly   302 WLLSQGKEERAKNILRRAAHVNK-RELPESVLDKL------VLANRDKLQQS-----SESRFP-I 353
            :||..|:.:|..:.:...:..|. |.|.|..:.:|      |...|.|..|:     .:...| :
  Fly   214 FLLMIGETKRGLDTMEWISRKNTGRTLSEDQMKRLLAYQEHVQVKRRKEHQNFFRSMLDDAMPLV 278

  Fly   354 REAFKNFKWRIANCSLCWIVHVL--------VYY---------------GLS------------- 382
            |:.:..:    ..| :|.::.||        ::|               |::
  Fly   279 RKPYGGY----FTC-VCMVMFVLGLLTHGLGIWYTAMRNRCNMRQGNTNGMTFCQVLFVPETGPF 338

  Fly   383 ------LNVVLLDGDK-YNN-----FAYIALVEIPG---FFMPLLIMDRFGRRYSLCGLMLASGL 432
                  |:||..|..| :|:     |.|:.|..|..   |.:...:|..|.        ::||.
  Fly   339 IETESDLDVVCSDSFKGFNDSFVLGFVYVVLYNISWASLFCVHKKVMFVFS--------LVASS- 394

  Fly   433 CCIGTIFTGADQPVLQL--VLFLV---GKLTITASFQVLYFFASEIYPTNLRNSL----LSFCSM 488
             ..|.:...|...:|||  ::||:   |.:.......:|.|     .||.||...    |.:|..
  Fly   395 -TFGFLLIFATNHMLQLFSLVFLIAFPGIIIGLLGGSLLVF-----VPTYLRGKALCISLMWCRC 453

  Fly   489 MGRFGSMLAPQTPLLAKYYANAPAMLFA------GAAIVSGLLTL 527
            ...||:||..     :|...|....|.|      .||.:.|.|.|
  Fly   454 GAAFGAMLVG-----SKIQYNCELFLLAISILPLIAACMEGYLPL 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	100/499 (20%)
		MFS	146..530	CDD:119392	100/499 (20%)
CG12783	NP_001262644.2	synapt_SV2	<2..>310	CDD:130366	56/295 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458217
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940