Protein Alignment SLC22A and CG6126

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 542
• Identity: 170/542 - (31%)
• Similarity: 263/542 - (48%)
• Gaps: 43/542 - (7%)

  Fly    24 DVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYEP 88
            |..|:.::..||:||::|.:.|.|..|..:...|..::.|..||...|||.:|..|    |....
  Fly     4 DYVLEDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVD----NSSLS 64

  Fly    89 HTNW-------SIP-KNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDDE 145
            .|.|       :|| |...:|:||..:..|. |..|.::          |.|...::...::...
  Fly    65 VTPWNSSAILAAIPLKPNGELESCLMFDPSS-PGTNTTI----------NCERYVYDTTYYKTSR 118

  Fly   146 VTISNDFGIFCDDEWKLSMVGTINNLGQFFG-IPIGGFVADRYGRSFSIALGGILGAVLGVIRSF 209
             ||  |:...||..|..::|.|:..||.|.| :.:|| :||:.||........:...::||..:|
  Fly   119 -TI--DWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGG-LADKVGRKTVFCWSALFQLIIGVGVAF 179

  Fly   210 SPSYGWFLVFEFLDNMTSST-LYSTCFVIGIELVGPKRRVLACSVITVFYAV--GEVLLAMSAKA 271
            .|.|..|:|..:|..:..|. .|...||:.:|||||.:|.: |.:  .|.||  |.::|.....|
  Fly   180 IPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTV-CGI--TFQAVFAGGIMLVAGWGA 241

  Fly   272 FHDWRILLRITYG-PSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKL 335
            ....|..|::.|| ...:.|.::|.|.||.|||..||:...|.:|:.:...:|...:|   :||.
  Fly   242 LIPDRQWLQVIYGLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIP---VDKE 303

  Fly   336 VLANRDKLQQSSE--SRFPIREAFK--NFKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNF 396
            ....:.|.|.::|  |...:.:.|:  |.:.:..|..|||..:.||||||||:...|.|:.|...
  Fly   304 YYVQKAKQQAAAEEKSSAGLSDLFRTPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLIL 368

  Fly   397 AYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITA 461
            ..:.|||.|.:...:.::||.|||.....|||..|||||...:. |........:.:.|||.|..
  Fly   369 FIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYI-AQGSTTSTAVVMAGKLLIAG 432

  Fly   462 SFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLT 526
            ||.|:|.:::|::||.:|||.:...||..|....|.|...||..:....||:||...|::||...
  Fly   433 SFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWV 497

  Fly   527 LFFPETTNVVLPTTVQEADAIG 548
            :|.|||.|..:|.::::.:..|
  Fly   498 MFLPETMNQPMPESIEDGENFG 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	131/402 (33%)
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	165/520 (32%)