Protein Alignment SLC22A and CG6006

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001097812.1
• Gene: CG6006 / 41962
• FlyBaseID: FBgn0063649
• Length: 603
• Species: Drosophila melanogaster
• Alignment Length: 543
• Identity: 146/543 - (26%)
• Similarity: 254/543 - (46%)
• Gaps: 38/543 - (6%)

  Fly     6 APPADPAVEVA--PPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICL---PMMFHAMFSVTYVFT 65
            |.|..||..|:  .|| |.||.| |.|...:|.:|::||::.:|:.|   |..||...|   ::.
  Fly    61 ATPQSPAAAVSGLDPA-DDEDET-DVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSS---IYQ 120

  Fly    66 AATVTHRCSVEECDLPGSNYYEPHTNWSIPKN-GKDLDSCNRYTNSELPQWNHSVDICS----AD 125
            ||....     .|..|....:.|...|   :| ...:|:|.|:...:..|.::...:.|    ..
  Fly   121 AANKDF-----WCQRPAQLQHMPVATW---RNLSGSVDNCRRWEGIDWSQVSNETTLPSDWKTPA 177

  Fly   126 HFTKNKEACAHNEFVFRDD-EVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGR 189
            ...|...||...|:...|: ..|.::.:.:.|:.|...::......||...|..|.|:::|::||
  Fly   178 EMDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGR 242

  Fly   190 SFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVI 254
            ...:.:..:|..:.|:......|:..:|....|..:.|.::..:..::.||.|..|.|.:| .:.
  Fly   243 KTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDGKWRTIA-GMY 306

  Fly   255 TVF-YAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFW-ILPESVRWLLSQGKEERAKNILR 317
            .:| ..:..::::..|....|:: .|::..|...|.|.:.| ::|||.||||.:|:.:..:.|:.
  Fly   307 NLFPLPISYMIISGLAYLTQDYQ-RLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIE 370

  Fly   318 RAAHVNKRELPESVLDKLVLANRDKLQQSSESRFPIREAFKNFKWRIANCSLC-WIVHVLVYYGL 381
            .||..|.|:||...  :|....::...|  :..:..|.::..   ||:.|..| |....|||||:
  Fly   371 AAAKFNGRQLPADY--QLTPPTQESSTQ--DVTYLFRSSYLR---RISICFFCIWFTMNLVYYGI 428

  Fly   382 SLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGL-CCIGTIFTG-ADQ 444
            .||:....|:.|.|.|...|||||...:.:.|:.:.|:::..|..::.:|: ||...|..| ||.
  Fly   429 ILNMSSFGGNVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATLICAGVACCCAAITEGHADL 493

  Fly   445 PVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYAN 509
            ..|::...::||.||:|...::..:.:|:|||.:||..:..|::......:|.|...||.|...:
  Fly   494 LWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALILTPYLSLLNKIEGH 558

  Fly   510 APAMLFAGAAIVSGLLTLFFPET 532
            ....|....:|..|.:.||.|||
  Fly   559 LLMTLLTAWSIFGGFVVLFLPET 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	105/399 (26%)
CG6006	NP_001097812.1	MFS_SLC22	189..579	CDD:340875	105/398 (26%)