Protein Alignment SLC22A and CG14857

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 135/560 - (24%)
• Similarity: 244/560 - (43%)
• Gaps: 67/560 - (11%)

  Fly    28 DAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATV-----THRCSVEECDLPGSNYYE 87
            |.||:..|..||:|.::.||     :.:..|:.|..:.:..:     .|.|           |:|
  Fly     4 DQILEKCGSAGRYQYLMILL-----LGYIAFTTTVHYYSQNIIGFVPQHWC-----------YHE 52

  Fly    88 PHTNWSIPK-------NGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACA----HNEFVF 141
            ...|.|..:       .||:. ||.|            :|....|..|.:.|.|.    :.:|.|
  Fly    53 ALENRSFEEIAAIYAPFGKEA-SCTR------------LDKIEGDRVTVSNETCQRWIYNYDFGF 104

  Fly   142 RDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVI 206
            |    :::.:....|:|.:|..:..::..||...|....|.:.||.||..::.|....|.|...:
  Fly   105 R----SMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFL 165

  Fly   207 RSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACS-VITVFYAVGEVLLAMSAK 270
            .:::.:...|.:|..:..:.::..|...|::.:|.:.||.|.:|.| .:.:.:.:|.::....:.
  Fly   166 TTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSV 230

  Fly   271 AFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLD-- 333
            ...:|||.|..:....|::..:::::.||.:||:::...|.|...|:..||.|..|:..:..:
  Fly   231 LAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAF 295

  Fly   334 -KLVLANRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHVLVYYGLSLNVVL--LDG---DK 392
             :..:..| ||....|....|.:..:....|  ..||. :|...:...||.|.:.  ::|   ..
  Fly   296 RRNCIVKR-KLSNQPEQTAGIFDLLRTPNLR--KVSLL-VVFTFMLTSLSFNTISRNVEGMGLSP 356

  Fly   393 YNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGL--CCIGTIFT--GADQPVLQLVLF- 452
            :..|:..|:|..|..|:..|:..|.||:.:....||.:||  |.:|...:  ||.:.|..|:.|
  Fly   357 FVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFA 421

  Fly   453 LVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAG 517
            |..:|.|:..:.|...||||:.||.:|:..::...:.....|.::|....|....|.||:::.|.
  Fly   422 LPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILAL 486

  Fly   518 AAIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKD 557
            ..:.:...||..|||.|..||.|:.:.:|.|..:...|.|
  Fly   487 LLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFD 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	97/407 (24%)
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	127/534 (24%)