Protein Alignment SLC22A and CG14856

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 120/540 - (22%)
• Similarity: 228/540 - (42%)
• Gaps: 42/540 - (7%)

  Fly    28 DAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATV-----THRCSVEECDLPGSNYYE 87
            |.||...|...|:|.::..|..|     .||.|:..:.|..|     .|.|..|:  |...:|.|
  Fly     6 DEILVKCGDSHRYQYMLLALYGL-----LMFIVSRHYFAQNVIGFVPDHWCYHEQ--LENRSYAE 63

  Fly    88 PHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDDE--VTISN 150
            ....::..|.    .||.|..:..:          ...:.|.:.|.|  |.:::..|.  ::::.
  Fly    64 IAAIYAPFKR----PSCTRLASINM----------DGSNATASSEPC--NRWIYHYDHGFISMNA 112

  Fly   151 DFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGW 215
            |....|||.:|..:..::..:|...|..:.|.:.||.||..::.|....|.:......|:.:...
  Fly   113 DLNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLT 177

  Fly   216 FLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSV-ITVFYAVGEVLLAMSAKAFHDWRILL 279
            |....|:..:.:.......|::.:|.|.|..|.:..:: :.|||.:|.:..:........||..:
  Fly   178 FSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSFM 242

  Fly   280 RITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKL-----VLAN 339
            ..|..|.|::..:::::.||.:||:::...:.|:..|||.|..|:|::.|:..:..     ...:
  Fly   243 VWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKES 307

  Fly   340 RDKLQQSSESRFPIREAFK--NFKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALV 402
            ..:.|.|.:.:..:.::||  ..:.|:...::.:.:..|.|..:|.||..|....:..|:..||.
  Fly   308 EARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVMFSLFALT 372

  Fly   403 EIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGT----IFTGADQPVLQLVLFLVGKLTITASF 463
            ..|.......:...|||:::....|.|:||....|    .|.......:.:.|.|:.:..|:.:.
  Fly   373 LPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFWTQHSATVMVCLLLMCRFGISVTT 437

  Fly   464 QVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLF 528
            ......::|:.||.:|:|.|:...:.....|.::|....|..|:..|.:::.....:||..:.|.
  Fly   438 GSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSIITCILLLVSAWICLL 502

  Fly   529 FPETTNVVLPTTVQEADAIG 548
            ..||.|..||.|:.|.:..|
  Fly   503 LSETRNKKLPLTLAEGEEFG 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	86/407 (21%)
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	114/523 (22%)