Protein Alignment SLC22A and CG14855

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 552
• Identity: 130/552 - (23%)
• Similarity: 238/552 - (43%)
• Gaps: 69/552 - (12%)

  Fly    28 DAILKHLGQFGRFQLII-----FLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYE 87
            :.||...|...|:|.::     :|::.:.|.:.:...:::|     ..|.|           |:|
  Fly     4 EEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFV-----PDHWC-----------YHE 52

  Fly    88 PHTNWSIPKNGK-----DLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDD--E 145
            ...|.|..:..|     :..||.|....:....||          |.::|.|  |.::::.|  .
  Fly    53 QLENRSFAEIEKIYSQFEKPSCTRLEKIDEDGQNH----------TLSRERC--NRWIYKYDFGY 105

  Fly   146 VTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFS 210
            .:::.:....||:.:|..:..::..:|...|....|.:.||.||..::.|....|.:......|:
  Fly   106 KSMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGFLGDFSTIFA 170

  Fly   211 PSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPK-RRVLACSVITVFYAVGEVLLAMSAKAFHD 274
            .|...|.:..|:..:.:.......:::.:|.|.|. |.|...:|:..||.:|.:.....|.....
  Fly   171 GSLTSFSISRFISGLAADANSYLMYILILEYVSPSLRNVGLNTVLGSFYCLGLIGACWLAVWVGH 235

  Fly   275 WRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDK----- 334
            |||.|..:..|.|::..:::::.||.:||:::...:.|...|.|.|.:|:|:    |.||
  Fly   236 WRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQ----VADKDFKDF 296

  Fly   335 -LVLANRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHVLV--YYGLSLNVVLLDGDKYNNF 396
             :......:..::.|....:.:..|..:.|.....|..|..::|  |..::.||..|....:..|
  Fly   297 RIYCEQHYRKDKNQEEHAKLLDMLKTPRMRSTAFKLLLIFIIIVPCYNTIARNVEGLGISPFIMF 361

  Fly   397 AYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIG---TIFTGADQPVLQLVLFLVGKLT 458
            :..||...|..::..|:.||.||:.:..|.|..:|:..:.   .|..|:::.    ||.||| ||
  Fly   362 SLNALTLPPSGYLQGLLQDRMGRKATAVGWMAITGIFAVAAGLVISQGSNRN----VLLLVG-LT 421

  Fly   459 ITASFQVLYF------FASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAG 517
            :.|.|.|...      |::|:.||::|...::...:.|...|.|:|....|..||..||:::. |
  Fly   422 MAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHLGTYYKPAPSIIL-G 485

  Fly   518 AAIVSG-LLTLFFPETTNVVLPTTVQEADAIG 548
            ...:|| .:.|..|||.|..||.::.|.:..|
  Fly   486 LLFLSGAYVCLLLPETRNKKLPMSLAEGEEFG 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	99/414 (24%)
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	124/533 (23%)