Protein Alignment SLC22A and CG44098

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001262264.1
• Gene: CG44098 / 40590
• FlyBaseID: FBgn0264907
• Length: 813
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 132/570 - (23%)
• Similarity: 240/570 - (42%)
• Gaps: 63/570 - (11%)

  Fly    16 APPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDL 80
            ||.........:||:.:..|.:|::||...|||.|..:..:.|....:|||....|  ....|..
  Fly   195 APKPNTKMQTKVDAVGQITGPWGKWQLRTVLLIFLCKIPSSWFMACIIFTAPAPRH--GEFFCKP 257

  Fly    81 PGSNYYEPHTNW---SIPKNGK------DLDSCNRYTNSELPQWNHSVDICSAD----------H 126
            |.:...:..|.|   |.|:..:      .:|.||.|.::: ...:|..:..::|          |
  Fly   258 PHTIGAQNQTQWIKVSHPQKEESDDQEFSIDFCNVYQDAQ-EHAHHYYNYENSDQEPRVWEKPLH 321

  Fly   127 FTKNKEACAHNEFVFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSF 191
            ...|...|  .||....|..::...:.:.|..:    ::.::......||:..||.:|::..:.|
  Fly   322 RNSNVIPC--TEFQHESDYHSVVTQYDLVCSRD----ILVSVTQFFHLFGVLTGGILANQLLKYF 380

  Fly   192 S---IALGGILGAVL-GVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACS 252
            |   :.|.|::..:. |.:.....||...:.|..|..:..:.:|:....|..::.|.|.|....:
  Fly   381 SPRNVMLFGMITQIFCGNLTGHVASYELHVFFRCLSAVCCAQMYTAGGQIMADITGGKYRTCVST 445

  Fly   253 VITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFW-ILPESVRWLLSQGKEERAKNIL 316
            :...|:::|.::|...|..:..|..|......|::||: |.| .:|:|.|||:::|:.:.||.||
  Fly   446 LFEQFWSIGVMMLPGVASFWSSWSHLYMAISWPTVILI-YLWQWIPDSPRWLIARGRTQDAKKIL 509

  Fly   317 RRAAHVNKR--ELPESVLDKLVLANRDKLQQSSESRFPIREAFKNFKWR-------IANCSLCWI 372
            .....||..  .||..:..:|      :||..:....|....:.:. |:       |....|.|.
  Fly   510 LECVEVNGTGYNLPHDIDQQL------ELQAQTAMDAPPPSGWWSM-WKGERAVRHIVCVHLAWS 567

  Fly   373 VHVLVYYGLSLNVVLLDGDK-YNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGL--MLASGLCC 434
            ::::||||:.||:.....|. |.|..:....|:.|.|..|.::.:..|::...||  ::|..:..
  Fly   568 LYIVVYYGMLLNIRSFSRDHLYINTFFAGFSEMMGTFFGLFLILKTTRKWLWTGLFNIVAGCIAY 632

  Fly   435 IGTI-----FTGADQPV-LQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSM-MGRF 492
            .|.:     ..|.|..| |.:...:|.|:.|:.:..:|.....|:...: :..:.||.:: ..||
  Fly   633 CGWLVPKPSVIGLDPNVALLMCSAMVSKMAISTTLSILTTCTVELVSDD-KKKITSFSTICWARF 696

  Fly   493 GSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLT--LFFPETTNVVLPTT 540
            ..:.||.......:....|...||..||:.||.|  :..|.|..:..|::
  Fly   697 WLLGAPFIGSTVVFGQLIPQTAFASLAILGGLCTSLISSPRTHPISRPSS 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	97/419 (23%)
CG44098	NP_001262264.1	MFS_SLC22	329..732	CDD:340875	98/417 (24%)