Protein Alignment SLC22A and CG42269

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_648019.2
• Gene: CG42269 / 38689
• FlyBaseID: FBgn0259164
• Length: 662
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 154/556 - (27%)
• Similarity: 255/556 - (45%)
• Gaps: 54/556 - (9%)

  Fly    17 PPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVF------TAATVTHRCSV 75
            ||:.|.:|     ||..:|:|||:|.::|  ||   |....|.|.:|:      |.....|.|.|
  Fly    67 PPSMDFDD-----ILPLIGEFGRYQKLLF--IC---MIPFSFFVAFVYFSQIFLTLIPEQHWCHV 121

  Fly    76 EECDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNK--------- 131
            .|.|  |.: .|.....|||....:.::|..|            |:...|...:.|
  Fly   122 PELD--GLD-VEARLALSIPMTNGEYNNCYMY------------DVNYTDILAQGKVMADPKWPQ 171

  Fly   132 EACAHNEFVFRDDEV---TISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSI 193
            ..|.|. :.:...|:   |::.:....|||....:...:|..||...|..:.|:||||:||..::
  Fly   172 VKCRHG-WSYNFTEIPYATVATEQNWVCDDAALPTYAQSIFFLGAIVGGLLFGWVADRFGRIPAL 235

  Fly   194 ALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSV-ITVF 257
            ....::|.:.||..:|..::..|.:..|.........::..:::.:|.||||.|....:: |.:|
  Fly   236 IGTNMMGLLAGVGTAFVSNFWEFAIMRFFVGFAFDNCFTMMYILVLEYVGPKYRTFVANMSIAIF 300

  Fly   258 YAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYF--WILPESVRWLLSQGKEERAKNILRRAA 320
            :.....||...|....||::|..:|..|  :|||.|  :::|||.|||:||||.::|..||::..
  Fly   301 FTGAACLLPWIAYFLADWKLLAIVTSAP--LLLAIFTPFVVPESARWLVSQGKVDKAVGILKKLE 363

  Fly   321 HVNKRELPESVLDKLV-LANRDKLQQSSESRFPIREAFKNFKWRIANCSL--CWIVHVLVYYGLS 382
            ..|.|::|........ ...|.:.|::...::.:.:.||:.:.|.....|  .|:...||:.|..
  Fly   364 KGNGRQVPPQTYQIFTDSCKRMQEQEAQNGKYSVLDLFKSPRLRRTTLLLIVIWMAISLVFDGHV 428

  Fly   383 LNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVL 447
            .||..|..|.:..|......|:|...:..:|:||||||:..|..|:.||:  ...:.|.....:.
  Fly   429 RNVGSLGLDIFFTFTLACFTELPADTLLTVILDRFGRRWLACSSMVLSGV--FSLLATVVPVGIY 491

  Fly   448 QLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPA 512
            ...|.::|:..:..|:.:...:|:|:.||.:|...::|..:||...|::||....||......|.
  Fly   492 SAALAIMGRFFVNISYNIGLQWAAEVLPTVVRAQAVAFIHIMGYVASIIAPFVVYLANISQALPL 556

  Fly   513 MLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIG 548
            ::.....|:.|||.|..|||.|.|||.|:.:.:..|
  Fly   557 IILGILGIIGGLLALLLPETLNHVLPQTLSDGEEFG 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	110/402 (27%)
CG42269	NP_648019.2	2A0119	80..552	CDD:273328	133/496 (27%)