Protein Alignment SLC22A and CG10486

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 151/570 - (26%)
• Similarity: 249/570 - (43%)
• Gaps: 64/570 - (11%)

  Fly    14 EVAPPAK--DSED-VTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSV 75
            |.:.|.:  :::| :..|.:|..:|||||||:.:||           |.:.:.|..|.| :...:
  Fly    80 ETSLPRRSWETDDYIDFDDLLPMIGQFGRFQIRLFL-----------FMIPFCFITAFV-YLGQI 132

  Fly    76 EECDLPGSNY-YEP---HT------NWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKN 130
            ..|..|...| |.|   ||      ..||||. ||    ..|:...:...|:     :..||.:|
  Fly   133 FMCLTPPKYYCYVPELLHTPVELRKELSIPKE-KD----GSYSRCRMYNTNY-----TKIHFAEN 187

  Fly   131 KEACAHNE---------FVFRDDEVTISN---DFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFV 183
            ..|..:..         :||..:.....:   :||..|||:...:....|..||...|....|..
  Fly   188 PSAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHF 252

  Fly   184 ADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRV 248
            ||..||..::.....|..|..:..|.|..:..|.:..||...:..|.::..:::.:|.||||.|.
  Fly   253 ADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRT 317

  Fly   249 LACSV-ITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERA 312
            |..:: :.:||:...:::...|.:..:||.....|..|.::.:..|.:||||.|||:|.|:.::|
  Fly   318 LVANLSLALFYSPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKA 382

  Fly   313 KNILRRAAHVNKRELPESVLDKLVLANRDKLQQSSESR-FPIREAFKNFKWRIAN----CSLCWI 372
            ..||:....|||:::.:.:||....:.....::..:.| |.:...||  :.|:|.    ..|.|:
  Fly   383 LEILKNVIEVNKKQVSKEILDLFEASCTQFYKEELDGRDFTVLSIFK--RKRMARYMILMILIWM 445

  Fly   373 VHVLVYYGLSLNVVLLDGDKYNNFAYIA-LVEIPGFFMPLLIMDRFGRRYSLCGLM---LASGLC 433
            ...|||.|......:||.:....|..|| ..|:||..:.:|.:||.|||:  |...   |:....
  Fly   446 SISLVYDGHVRAASVLDSENIFLFFTIACATELPGNILVILTLDRAGRRW--CSFFYTSLSGVFS 508

  Fly   434 CIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAP 498
            .:|..|.......:..   |.|:......:.:...:|:||.||.:|...::|...||....:::|
  Fly   509 LLGASFQNRANMRMSA---LAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSP 570

  Fly   499 QTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIG 548
            ....|:|...::..::.....|..|||.||.|||.|..||.|:.:....|
  Fly   571 PVVYLSKKSLSSTLIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFG 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	106/415 (26%)
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	144/536 (27%)