Protein Alignment SLC22A and T22F7.1

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_497209.1
• Gene: T22F7.1 / 3564822
• WormBaseID: WBGene00020701
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 444
• Identity: 108/444 - (24%)
• Similarity: 204/444 - (45%)
• Gaps: 45/444 - (10%)

  Fly   115 WNHSVDICSADHFTKNKEACAHNEFVFRDDEVTISNDFGI----FCDDEWKL-SMVGTINNL--G 172
            |:    :|:....:....|.|.:|........||.|:|.:    |..:..:| :.:..:.||  |
 Worm    84 WS----LCALSAISPAFTAPAGDECTENCSFYTIQNEFNLTSKFFLVEPAELTTSIYFLGNLLIG 144

  Fly   173 QFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVI 237
            |.|.:     ||||:||...|.:..:|..::|.:.|.:|::...||..|:.....:.|.:..:|:
 Worm   145 QLFAV-----VADRFGRRPIIIICLLLTGIVGSLGSLAPNFPLLLVARFIQGSCYTPLTTVNYVL 204

  Fly   238 GIELVGPKRRVLACSVITVFYAV----GEVLLAMSAKAFHDWRILLRITYGPSLILLAYFWI--L 296
            ..|.: |.|   :.|:.::|:.|    |...||..:..|:.||.|...|..|: ||:|.|.:  |
 Worm   205 SGESI-PHR---SQSLTSIFFGVSWVCGYCFLAPLSVWFNTWRSLQLATALPN-ILVAVFLMGTL 264

  Fly   297 PESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQQSS----ESRFPIREAF 357
            ||||.:.:.:...:..:..::|...::.::|... || :::...:|:..||    ::|..|.|..
 Worm   265 PESVGYSIEKKNRKAVQKWIKRNELLSCKKLNYD-LD-MIMEKTEKIATSSSPTPQNRLTIFEMI 327

  Fly   358 ------KNFKWRIANCSLCWIVHVLVYYGLSLNVVLL-DGDKYNNFAYIALVEIPGFFMPLLIMD 415
                  :....||...:..||:..:.|..|||....: :.|...:|.:..:||:|.:....:.:.
 Worm   328 REILSDREITRRIIVETFLWILTFMTYCALSLTSTSVGNSDPLVSFLFSGVVELPAYLFIPICLT 392

  Fly   416 RFGRRYS--LCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNL 478
            |..||.:  ||..   :|...:.|::..::...|.|:::||.|...:..:...:.:|:|::||..
 Worm   393 RTKRRPTRFLCHF---TGSMALLTMYFLSNDTSLHLIIWLVAKFCASCCYIFCFIYAAELFPTWC 454

  Fly   479 RNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPET 532
            |:..:..||.....|:::||...|:......|..::.|...::...||....||
 Worm   455 RSCCIGVCSTCCNIGAIVAPHIFLIDSAAPGAQFLVLAAVGLLCSGLTWCQQET 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	108/444 (24%)
		MFS	146..530	CDD:119392	101/409 (25%)
T22F7.1	NP_497209.1	MFS_SLC22	101..505	CDD:340875	102/418 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163059
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.666667	Normalized mean entropy	S2472
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.900