Protein Alignment SLC22A and CarT

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 591
• Identity: 175/591 - (29%)
• Similarity: 264/591 - (44%)
• Gaps: 82/591 - (13%)

  Fly     7 PPADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMF-SVTYVFTAATV- 69
            |.:.|:|:        |...||.:|..:|:||::|.::...||||......| :...:|.|.|.
  Fly    24 PESQPSVD--------EAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPD 80

  Fly    70 THRCSVEE-CDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSEL---------PQWNHSVDICSA 124
            .:.|.:.| .|||    .|...:.|||   |:||      |.||         ..|...::....
  Fly    81 DYWCRIPELLDLP----LEQRKSLSIP---KELD------NDELVYSKCYTYGVNWTQLLESGEE 132

  Fly   125 DHFT-----------KNKEACAHNEFVFRDDEVTISNDFGIFCDDEWKLSMVGTIN----NLGQF 174
            |..|           |..:...:|..|...   :|..||.:.||.:    :..||.    |.|..
  Fly   133 DDLTTMEPNASWPLIKCPQGWEYNTSVVWS---SIVIDFDLVCDQD----IYPTIGLAALNTGGP 190

  Fly   175 FGIPIGGFVADRYGR--SFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVI 237
            .|:.:.|.:.||.||  |:.:.|..:|...|  :.|.|..:..:.....:..:|...:|...|:|
  Fly   191 VGVYLFGLLNDRGGRRLSYFVCLATLLAGSL--MTSLSKDFWTWAGSRVIVGLTIPAVYQIPFII 253

  Fly   238 GIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYF---WILPES 299
            .:||||...|.....:...||..|.:||:.......||   :|::|..||...|||   :::|||
  Fly   254 SLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYLERDW---VRLSYITSLPFYAYFLYMFVMPES 315

  Fly   300 VRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKL-VLANRDKLQQSSES----------RFPI 353
            .||||.:|:.|.|..||.|.|.||.||.||:|..|| ....||||::..:.          |.|
  Fly   316 PRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTP- 379

  Fly   354 REAFKNFKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFG 418
                 |.:.:....:|.|..:..||.|||.....|..::|.:|...|:||:|.:......||.:|
  Fly   380 -----NMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWG 439

  Fly   419 RRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLL 483
            ||:.|...|:..|:.|:.|:....|.....|||:||.|..::|||.::|.||.|:|||.:|...:
  Fly   440 RRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGI 504

  Fly   484 SFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIG 548
            ...|.:|..|.:..|....|.|.....|.::....:::.|:..|..|||.:..||.|::|.:..|
  Fly   505 GASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFG 569

  Fly   549 VKKQSK 554
            ...|.|
  Fly   570 KNWQFK 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	127/413 (31%)
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	127/416 (31%)
		xylE	<306..>342	CDD:182225	17/35 (49%)