Protein Alignment SLC22A and CG31272

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_650013.3
• Gene: CG31272 / 326130
• FlyBaseID: FBgn0051272
• Length: 563
• Species: Drosophila melanogaster
• Alignment Length: 635
• Identity: 126/635 - (19%)
• Similarity: 211/635 - (33%)
• Gaps: 217/635 - (34%)

  Fly     9 ADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMF---SVTYVFTAATVT 70
            :|...|......:....|.|..::..| ||.|.|:: |::.:|....|:|   |::|:...|
  Fly    27 SDSTAEAEATPTEEGSATFDKAIEGAG-FGIFNLML-LIVSIPAQSAAIFESSSMSYILPIA--- 86

  Fly    71 HRCSVEECDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACA 135
                  ||||
  Fly    87 ------ECDL------------------------------------------------------- 90

  Fly   136 HNEFVFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIG----GFVADRYGRSFSIALG 196
                     .:|: .|.|:.              |...:.|:.|.    |::||..||...:..|
  Fly    91 ---------RLTL-EDKGVL--------------NAVAYAGMTISAIAWGYLADTKGRKKILYWG 131

  Fly   197 GILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVG 261
            .::.||.....:.|.::...::|:||..:..:...:..|....|:.|||.|.....::.:..:..
  Fly   132 YLIDAVCVFGSALSQNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSVLMIVGMVTSTA 196

  Fly   262 EVLLAMSAKAF--------------HDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERA 312
            .|.|.:.|...              |.|:|.|.:...||||....|..:|||.|:|::||:.|.|
  Fly   197 TVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPESPRFLMAQGRNEEA 261

  Fly   313 KNILRRAAHVNKRELPESVLDKLVL---ANRDKLQ------------------QSSESRFPIREA 356
            ....::..|||.|:..:|...|.::   .||...|                  ||......:|..
  Fly   262 LQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTKRQSRTLAESLRAG 326

  Fly   357 FKNFK-------WRIANCSLCWIVHVLVYYGLSLNVVLL------------------DG------ 390
            .:..|       ..:|.|  |:::...::.|  :|.:.|                  ||
  Fly   327 LQQMKPLVRKPLLGLAIC--CYVMQFGIFLG--MNTIRLWLPQLFASMAEYEALHAGDGLDVSMC 387

  Fly   391 -----------------------------DKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGL 426
                                         |.|.|...::.....|:|....|:...|.:     .
  Fly   388 TILEFSVNQTAETALNYADACSEPKVISMDMYLNNIIVSATGFVGYFFAGGILRALGPK-----R 447

  Fly   427 MLASGLCCIGTIFTGADQPVLQLVLFLVGK--LTITA-SFQVLYFFASEIYPTNLRNSLLSFCSM 488
            |:..||...||........|..|:..:|..  ||||. :...|......::||.||..:::...|
  Fly   448 MMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLTITGIAVSSLLGAVVALFPTQLRTVVVAIAMM 512

  Fly   489 MGRF----GSMLAP---QTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPE 531
            .|||    |::|.|   ||..|      .|.::.:...|:||:|::..|:
  Fly   513 CGRFGALSGNLLFPVFVQTGCL------PPFIMVSSVLILSGILSISLPD 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	122/609 (20%)
		MFS	146..530	CDD:119392	105/492 (21%)
CG31272	NP_650013.3	MFS	62..555	CDD:119392	116/595 (19%)
		2A0115	74..524	CDD:273327	103/546 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940