Protein Alignment SLC22A and CG15221

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001096957.1
• Gene: CG15221 / 32127
• FlyBaseID: FBgn0030331
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 103/505 - (20%)
• Similarity: 187/505 - (37%)
• Gaps: 146/505 - (28%)

  Fly   156 CDDEWKLSMVGTINNLGQFFGIPIG----GFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWF 216
            ||.:..|:..|.:.:.| |.|:.:.    ||:||.:||:.::.....:.:|..::.:||.:....
  Fly    77 CDLQPTLNQQGILASAG-FLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWML 140

  Fly   217 LVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVF----------YAVG-------EVL 264
            :||.||.....|...:..|.:..|..|...|:...::::.|          .|:|       .::
  Fly   141 IVFRFLTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIV 205

  Fly   265 LAMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPE 329
            |.|.   |..||:||.......|:.|.....|||:.::||.||:.:.:..:||.
  Fly   206 LGMH---FSSWRVLLLANVSIPLLALVGISALPETPKYLLVQGRGDESLEVLRS----------- 256

  Fly   330 SVLDKLVLAN---RDKLQQSSESRFPIREA------------------------------FKNFK 361
                  :.||   ||      .|.:|::|.                              ::...
  Fly   257 ------IFANNSGRD------PSEYPVKEVALESGGVSLSDVHGFLDAVRLVWHQTVPLFYRARL 309

  Fly   362 WRIAN-CSLCWIVHVL---------------------------VYYGLSLN----------VVLL 388
            |...| |.:.:|::.|                           |..|.::|          .|.:
  Fly   310 WHTLNICCIQFIIYFLAQGIFMWFPTILDELGTRNGENTLLCTVLQGFNINSSSEDEASSCSVEV 374

  Fly   389 DGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLVLFL 453
            |...|.....||...:..:.:...|:|..|::..|...|:.:.:|.:...:      |.|..|.:
  Fly   375 DTSTYQVMIIIAACFVVIYLIFAYIIDYMGKKNLLMAWMVLTMICLVALHY------VEQFALVV 433

  Fly   454 VGKLTITASF----QVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAK-YYANAPAM 513
            :. ||:..:.    .::...|.|.|||::....:.|..|:||.|:::.  :.:|.: .:|:...:
  Fly   434 IA-LTVVMAIGNCGGLVSTIAMEFYPTHINAMGMCFIMMVGRLGAVVG--SNILGRLLFASCDPI 495

  Fly   514 LFAGAAIVSGLLTL--FFPE-----------TTNVVLPTTVQEADAIGVK 550
            .:|..|:|..|.||  |.||           |...::..|.....||..|
  Fly   496 FWALLALVVLLCTLGYFLPEKARSQQKKPSATAKAIVTATTSPIFAINSK 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	96/472 (20%)
CG15221	NP_001096957.1	2A0119	<85..479	CDD:273328	84/427 (20%)