Protein Alignment SLC22A and CG31106

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_733086.2
• Gene: CG31106 / 318594
• FlyBaseID: FBgn0051106
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 620
• Identity: 139/620 - (22%)
• Similarity: 220/620 - (35%)
• Gaps: 201/620 - (32%)

  Fly     3 ASEAPPADPAVEVAPPAKDS-------EDVTLDAILKHLGQFGRFQLIIFLL--ICLPMMFHAMF 58
            :||:...|  ||..|.:..|       |||     |:.:| |||.|.|:...  :.|.|:.:...
  Fly     2 SSESGQQD--VESKPKSARSTSAGHEYEDV-----LQIIG-FGRVQWIVLFAAGLLLMMVINETM 58

  Fly    59 SVTYVFTAATVTHRCSVEECDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVD--I 121
            .::|:    |:..:|..|                                       .:|:|  :
  Fly    59 GMSYI----TIVSQCDFE---------------------------------------MNSMDKAV 80

  Fly   122 CSADHFTKNKEACAHNEFVFRDDEVTISNDFGIFCDDE-WKLSMVGTINNLGQFFGIPIGGFVAD 185
            .||..|                        .||||... |                    |:::|
  Fly    81 MSAASF------------------------IGIFCSSYFW--------------------GYLSD 101

  Fly   186 RYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVF-----EFLDNMTSSTLYSTCFVIGIELVGPK 245
            ..||...:....|.|..|.:..:..|:| |..||     .|.....|||.|:   .:| |...|:
  Fly   102 TIGRRPVLIYTTIAGNFLSLCSTVIPNY-WLYVFIRFGVGFFIAGASSTTYA---YLG-EFFTPR 161

  Fly   246 RRVLACSVITVFYAVGEVLLAMSA---------------KAFHDWRILLRITYGPSLILLAYFWI 295
            .|.:|.:..::|..|..|.:..:|               .:...||:|......|.::.....|.
  Fly   162 HRPIAINYASLFVGVSTVYVPATAWLILSMDWSVSITDGFSLRPWRLLTICYLLPGVVGTLMLWS 226

  Fly   296 LPESVRWLLSQGKEERAKNILRRAAHVNK-RELPESVLDKLVL---ANRDKLQQSSESRF-PIRE 355
            ||||.:.|:|..|.|.|...:...|..|. :.|.|..:.||..   ||.:.:...|:|.| .|::
  Fly   227 LPESPKILMSLHKTEEAFAAVDWIAVTNSGKHLHEFKVHKLKTEDNANGENILLISKSAFTTIKK 291

  Fly   356 AFK------------NFKWRIANCS-LCWIVHVLVYYGL----------------SLNVV-LLDG 390
            .:|            ||   :.:|: :|.:.......||                |:.|. ::|.
  Fly   292 MWKETLPLLRRPHLLNF---VISCTIMCGLFFSSSGMGLWYPEIQNRLGSNAADDSMTVCQVIDA 353

  Fly   391 ---------------DKYNNFAYIALVE-----IPGFFMPLLIMDRFGRRYSL-CGLMLASGLCC 434
                           |..|..:||..:.     |.|:.:..|:::..||:.|: .||.|| |.|.
  Fly   354 SIDQMQANASNKICDDHINTKSYIDTITYGSALIVGYILMGLVINTIGRKASISIGLTLA-GACA 417

  Fly   435 IGTIFTGADQPVLQ---LVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSML 496
            |..||...:..::.   |.|.|.|......|..|:     ::.||:||...:..|.|:||.||:.
  Fly   418 IALIFIKDEVAIVVCFCLYLVLPGLCVSILSGAVV-----DLVPTHLRGKAVCICLMLGRTGSVF 477

  Fly   497 APQ-TPLLAKYYANAPAMLFAGAAIVSGLLTLFFP 530
            ... ..:|.:.|.:....:|:|..:|...|||..|
  Fly   478 GSNIIGVLLESYCSLTFGVFSGFVLVCASLTLLLP 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	128/581 (22%)
		MFS	146..530	CDD:119392	110/464 (24%)
CG31106	NP_733086.2	2A0115	37..486	CDD:273327	116/549 (21%)
		MFS	40..512	CDD:119392	122/572 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458211
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940