Protein Alignment SLC22A and CG3168

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001284957.1
• Gene: CG3168 / 31612
• FlyBaseID: FBgn0029896
• Length: 632
• Species: Drosophila melanogaster
• Alignment Length: 561
• Identity: 123/561 - (21%)
• Similarity: 218/561 - (38%)
• Gaps: 128/561 - (22%)

  Fly    86 YEPHTNWSIPKNGKDLDSCNRYTNSELPQWNH------------------SVDICS-----ADHF 127
            |||.::    .|||..|     ...:.|...|                  ||.:..     ..:|
  Fly    82 YEPDSH----ANGKQQD-----VERDAPDGGHGGHGPPGKGGKGGKGRKKSVPLPEPTAPIVANF 137

  Fly   128 TKNKEACAHNEF----------VFRDDEV-TISNDF---GIFCDDEWKLSMVGTINNLGQFFGIP 178
            .:..|.|.:.:|          |...:|: .||..|   ...||.:......|.:|:: .|.|:.
  Fly   138 ERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSI-IFIGMM 201

  Fly   179 IG----GFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGI 239
            :|    |.:||.:||...:.:...:.|...|..|||.:|.:|::|.||:...........:....
  Fly   202 VGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFA 266

  Fly   240 ELVGPKRRVLACSVITVFYAVGEVLLAMSA--------------KAFHDWRILLRITYGPSLILL 290
            |.....:|....|.:..|:..|.:.:|..|              ..::.|||.|.:...||.::.
  Fly   267 EFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVG 331

  Fly   291 AYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVL-------DKLVLANRDKLQQSSE 348
            ...:.||||.::||::||::||..|.|.....|.:..|:..:       :||:.:|.:...:.|.
  Fly   332 FLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYSR 396

  Fly   349 SRFPI----REAFKN--FKWRIANCSLCWIVHVLVYYGLSL------------------------ 383
            ....:    |..||:  .::.|.:.::.:..|: .||||.:
  Fly   397 MISGMVDHSRALFKSPILRFTIVSITINFTFHI-GYYGLLMWFPELFNRFEEYEKAFPDQSAGVC 460

  Fly   384 ----NVVLLDGDKYNN-------------FAYIALVE-IPGFFMPLLIMDRFGRRYSLCGLMLAS 430
                .||.|..::.||             .:.|:|.. :|...:.:|.||..||::.|....:.:
  Fly   461 AVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTA 525

  Fly   431 GLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSM 495
            |:|.....|..:.  |..||:..:....|:|:...|....:|::||.||.:.::...:..|.|.:
  Fly   526 GICSALMYFVRSS--VQNLVVSAIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGI 588

  Fly   496 LAPQTPLLAKY---YANAPAMLFAGAAIVSGLLTLFFPETT 533
            :.  ..::|:.   |..:|..:.:|..|..||:.|..|.||
  Fly   589 IG--NIVIAQLLDNYCPSPTFIVSGLLIGGGLMCLLLPNTT 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	123/561 (22%)
		MFS	146..530	CDD:119392	103/463 (22%)
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	99/454 (22%)
		MFS	154..623	CDD:119392	105/474 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010