Protein Alignment SLC22A and Slc22a13

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001119757.1
• Gene: Slc22a13 / 316062
• RGDID: 1306840
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 158/532 - (29%)
• Similarity: 254/532 - (47%)
• Gaps: 39/532 - (7%)

  Fly    30 ILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYEPHT---- 90
            ::..:|.|||||:.:.:|:.:|....|.|..:.||......|.|||        ::.:.||
  Rat     7 VMAEVGDFGRFQVRLTILMGIPNFLSAFFVFSQVFMVLDEAHYCSV--------SWVKNHTFNLS 63

  Fly    91 -----NWSIPKN--GKDLDSCNRYTNSELPQWNHSV-DICSADHFTKNKEACAHNEFVFRDDEVT 147
                 ..|||.:  |:. :||..:   ..|..|.|: ||.|  |.....:||........:...:
  Rat    64 AAEQLAVSIPNDTAGRP-ESCLMF---RPPPDNASLEDILS--HRFNETQACDSGWDYPENRPPS 122

  Fly   148 ISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPS 212
            :.|:|.:.|:.|.......::...|...|..:.|.|.|..||..|:.:..:|..:..:..:|..|
  Rat   123 LKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRPSLLMQLLLSGIASMATAFVSS 187

  Fly   213 YGWFLVFEF-LDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWR 276
            :..::...| |....:..|.|:..::. |.||..||..|..:....:|:|.:.||..|....:||
  Rat   188 FELYMTLRFALATANAGFLLSSNVLLS-EWVGTSRRTRAMVLAQSNFALGLMALAGLAYGVRNWR 251

  Fly   277 ILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRD 341
            :|..|...|..:|:.|||:||||.|||||||:.|.||.::::||.||.|.|...:|::||   .:
  Rat   252 LLQIIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLASELLNQLV---PE 313

  Fly   342 KLQQSSESRFPIREAFKNFKWRIANCSL--CWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEI 404
            |...|..:    .:.|::.:.|.....|  .|.|..|:||||...|.....|.|.......:||:
  Rat   314 KTGPSGNA----LDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQVIFGVVEV 374

  Fly   405 PGFFMPLLIMDRFGRRYS-LCGLMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYF 468
            |.....:.:|::.||::| ||.|.|| |:.|:..||...|.|.:...|.:|||...:|:|.:.|.
  Rat   375 PARLSSIPMMEKLGRKWSQLCTLTLA-GVMCVIIIFIPGDLPTVATALAVVGKFASSAAFTISYV 438

  Fly   469 FASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETT 533
            :.:|:.||.:|.:.:...|:..|.|.::.|...||.:|:...|.::|....|.:|||....|||.
  Rat   439 YTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPETR 503

  Fly   534 NVVLPTTVQEAD 545
            ...|..|:|:.:
  Rat   504 GQTLKDTLQDLE 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	119/397 (30%)
Slc22a13	NP_001119757.1	MFS_OAT	102..500	CDD:340932	121/406 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	515..537		0/1 (0%)