Protein Alignment SLC22A and Slc22a15

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001101177.1
• Gene: Slc22a15 / 310732
• RGDID: 1311184
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 157/546 - (28%)
• Similarity: 239/546 - (43%)
• Gaps: 96/546 - (17%)

  Fly    34 LGQFGRFQL-IIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYEPHTN------ 91
            :|:.|.:|: :.|||..|..::.|..::......||..:...:.|. ||.    :.|:|
  Rat    10 VGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYHWDMAEL-LPN----QSHSNQSSGKG 69

  Fly    92 -----WSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDDEVTISND 151
                 |.:..||.::.....::||                ||                  :|:::
  Rat    70 QAFGDWLLTANGSEIHKHVHFSNS----------------FT------------------SIASE 100

  Fly   152 FGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWF 216
            :.:..:..:|:|...:....|.|.|:...|.::||:||......|..|..:..:...|||||.:|
  Rat   101 WFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFF 165

  Fly   217 LVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRI 281
            .|..||..|.:..:....||:..|.||.....||.|:..:|:|||....|:.......||.|..:
  Rat   166 AVTRFLVGMMNGGMSLVAFVLLNECVGAAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAIL 230

  Fly   282 T--YGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQ 344
            .  .|..:.||:.|  :|||.|||.|||:...|:..|...|..|:                 ||:
  Rat   231 VNLQGTVVFLLSLF--IPESPRWLYSQGRLSEAEEALYLIAKRNR-----------------KLK 276

  Fly   345 QSSESRFPIREAFKN-------FKWRI-----ANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNFA 397
            .:.....|...:::.       |::|:     ......|.|..||||||:|:...|.|..|.|.|
  Rat   277 CTFSLTHPANRSYRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLA 341

  Fly   398 YIALVEIPGFFMPL---LIMDR-FGRRYSLCGLMLASGLCCIGTIF------TGADQPVLQLVLF 452
            ...|:|||.:  ||   ||..| |||:.:|...:...||.|:..:|      ||....|....|.
  Rat   342 LSGLIEIPSY--PLCIYLINQRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLS 404

  Fly   453 LVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAG 517
            |:|||||:|:|.::|.:.||:|||.:||..|..|||..|.|.::||..|.|.....:.|.::|..
  Rat   405 LLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFVPSLKDVQWSLPFIVFGA 469

  Fly   518 AAIVSGLLTLFFPETTNVVLPTTVQE 543
            ..:.||||:|..|||.|..|..|..:
  Rat   470 TGLTSGLLSLLLPETLNSPLLETFSD 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	129/417 (31%)
Slc22a15	NP_001101177.1	MFS_SLC22A15	71..469	CDD:340935	131/452 (29%)