Protein Alignment SLC22A and Slc22a17

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_803156.3
• Gene: Slc22a17 / 305886
• RGDID: 631405
• Length: 627
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 138/595 - (23%)
• Similarity: 233/595 - (39%)
• Gaps: 130/595 - (21%)

  Fly    16 APPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAM-FSVTYVFTAATVTHRCSVEECD 79
            |||.    .::.:|:|..:|..|..|.:...|.|||::|.|: .:...:||.|...| |......
  Rat    69 APPG----PLSFEALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIFTLAPPLH-CHYGALP 128

  Fly    80 LPGSNYYEPHTNWSIPKNGKDL-------------DSCNRYTNSELPQWNHSVDICSADHFTKNK 131
            ...|.:.:|..:..:...|..|             .||:.:..   |.:||    |..|
  Rat   129 PNASGWEQPPNSSGVSVAGAALAASAASRVVTSTDPSCSGFAP---PDFNH----CLKD------ 180

  Fly   132 EACAHNEFVFRDDEVTISNDFG---IFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSI 193
                   :.:....|..:|..|   :.||..|::.:...:..||...|....|:.|||:||...:
  Rat   181 -------WDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIV 238

  Fly   194 ALG-GILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRV---LACSVI 254
            .|. |::|. .||..:.:.|....:...||.....:.:....:::.:||..|.:|:   ||..::
  Rat   239 LLTLGLVGP-CGVGGAAAGSSTGIMTLRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELV 302

  Fly   255 TV---FYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFW--ILPESVRWLLSQGKEERAKN 314
            .|   |..:|   ||:.:|   |||.|.|:...|.::.|.|.|  :..||.|||:.:.:.|.|::
  Rat   303 GVGGHFLFLG---LALVSK---DWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQS 361

  Fly   315 ILRRAAHVNK---RELPESVLDKL-VLANRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHV 375
            :||..|..|:   :.|.|...:.| .|.|...|..:|...|.....::|. |:
  Rat   362 VLRILAERNRPHGQMLGEEAQEALQELENTCPLPTTSTFSFASLLNYRNI-WK------------ 413

  Fly   376 LVYYGLSLNVVLLDGDKYNNFAYIAL----VEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIG 436
                    |:::|.   :.||...|:    ..:.|...|        ..:.||.| ||||...:.
  Rat   414 --------NLLILG---FTNFIAHAIRHCYQPVGGGGSP--------SDFYLCSL-LASGTAALA 458

  Fly   437 TIFTGAD------QPVLQLVLFLVGKLTIT-------------ASFQVLYFF------------A 470
            .:|.|..      :.:|.|.:.|.|..::.             .:|.||..|            |
  Rat   459 CVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNDAAITTFSVLGLFSSQASAILSTLLA 523

  Fly   471 SEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNV 535
            :|:.||.:|...|.....:|..|.:..|...|...:.|....::.|..|::..|..:..|||...
  Rat   524 AEVIPTTVRGRGLGLIMALGALGGLSCPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRK 588

  Fly   536 VLPTTVQEAD 545
            :||..:::.:
  Rat   589 LLPEVLRDGE 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	103/444 (23%)
Slc22a17	NP_803156.3	MFS_SLC22A17	170..583	CDD:341003	108/472 (23%)