Protein Alignment SLC22A and Slc22a19

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_659034.1
• Gene: Slc22a19 / 207151
• MGIID: 2442751
• Length: 551
• Species: Mus musculus
• Alignment Length: 579
• Identity: 153/579 - (26%)
• Similarity: 253/579 - (43%)
• Gaps: 75/579 - (12%)

  Fly    28 DAILKHLGQFGRFQLI--IFLLICLPMMFHAM---FSVTYVFTAATVTHRCSVEECDLPGSNYYE 87
            |.|:: :|..||||::  ||:|||     ||:   .::...||||..:|||.|...|
Mouse     5 DLIIQ-IGSLGRFQILHMIFVLIC-----HALSAPHTLLENFTAAIPSHRCWVPILD-------- 55

  Fly    88 PHTNWSIPKNGK------DL-------------DSCNRYTNSELPQWNHSVDICSADHFT----- 128
               |.:...||.      ||             |.|.||..   ||| |.:      |..
Mouse    56 ---NDTASDNGSRILSQDDLLRISIPLDSNLRPDKCRRYIQ---PQW-HLL------HLNGTFPT 107

  Fly   129 ---KNKEAC----AHNEFVFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADR 186
               .:.|.|    .:::..|....||   .:.:.|..:...|:...|...|.|.|..:||.::|:
Mouse   108 VTEPDTEPCVDGWVYDQSTFLSTTVT---QWDLVCGSQALNSVAKFIYMTGIFIGYIMGGHLSDK 169

  Fly   187 YGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLAC 251
            :||........:..|:.....:|:||:..:....||..:.||||.:...::.:|...||.:.|..
Mouse   170 FGRKLIFTCSLLKMAITETCVAFAPSFLIYCSLRFLSGIFSSTLRTNSALLILEWTSPKFQALVM 234

  Fly   252 SVITVFYAVGEVLLAMSAKAFHDWRIL-LRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNI 315
            ::|.:...||:.||...|.||.:|..| |.::....|:|:...| |.||.|||:...|.:::...
Mouse   235 ALIFIASGVGQTLLGGLAFAFRNWHHLQLALSVPMFLLLIPTRW-LSESARWLIMANKPQKSLKE 298

  Fly   316 LRRAAHVN--KRELPESVLDKLVLANRDKLQQSSESRFPIREAFK--NFKWRIANCSLCWIVHVL 376
            |::||.||  |.......|:.:....:::|:.:.....|: :.|:  |.:.||...|....|.|:
Mouse   299 LKKAACVNRIKNSGDALTLEVVKTIMKEELEAAQTKPSPL-DLFRTPNLRKRICLLSFVRFVSVM 362

  Fly   377 VYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTG 441
            ...||.:|:..|..:.:.......:|.||...:....|:..|||.:....|...|:..:..:|..
Mouse   363 SLLGLLINIQYLSNNVFLLQCLYGVVCIPANVLGNFSMNYMGRRMTQLIFMSVLGISILAVVFLP 427

  Fly   442 ADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKY 506
            .:..:|::.|..:|....:||.......|:|:.||.:|.:.|....:.|..|..|:|...:|..|
Mouse   428 QEMQILRVFLSTLGGAISSASITSTLVHANELVPTIIRATALGVVGIAGSAGGALSPLLMILTTY 492

  Fly   507 YANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKDLDLVVTAT 565
            .|:.|.:::.....:.||:.|..|||.|..||.::|:.:  ..:|.||....|:|...|
Mouse   493 SASLPWIIYGILPFLGGLVALLLPETKNQPLPDSIQDIE--NKRKSSKEAKKDVVAKVT 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	101/398 (25%)
Slc22a19	NP_659034.1	MFS_OAT	109..516	CDD:340932	103/411 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..551		8/28 (29%)