Protein Alignment SLC22A and Y57G11C.23

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_502801.2
• Gene: Y57G11C.23 / 190377
• WormBaseID: WBGene00013318
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 131/603 - (21%)
• Similarity: 214/603 - (35%)
• Gaps: 167/603 - (27%)

  Fly    38 GRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYEPHTN-----WSIPKN 97
            |.::|.|.|:|...|..  .|||..:|....                .|.|.|:     :.....
 Worm     6 GAWRLDIGLMILYQMTL--FFSVQMLFVIFL----------------EYMPKTHCTEDRYCYKLK 52

  Fly    98 GKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEAC--AHNEFVFRDDEVTISNDFGIFCDDEW 160
            .|.:...:|:::|         |:|  ...:.|.:.|  |.|:..|...:.....|    |.. .
 Worm    53 NKCMSDFDRHSDS---------DVC--PFASTNFDQCVVAANKTDFYSAQYEYQQD----CTG-L 101

  Fly   161 KLSMVGTINNLGQFFGIPIGGFVADRYGRS----FSIALG---GILGAVLGVIRSFSPSYGWFLV 218
            |.....|...||...|..|.|:::|..||.    |||.||   .||.|.|..:.|       |.:
 Worm   102 KYFSSSTSTFLGTLVGNLILGYLSDTIGRRPVYIFSILLGVPSVILSAALNDVMS-------FYI 159

  Fly   219 FEFLDNMTSSTLYSTCFVIGIELVGPKRRV----------LACSVITVFYAVGEVLLAMSAKAFH 273
            |.||.....:...:..:....|:|.|.||.          .....:.|.:..||
 Worm   160 FRFLVGFAIAGTLTVGWTYASEMVIPSRRFRLRTFPNWANARMMQVGVSWLAGE----------- 213

  Fly   274 DWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLA 338
             ||:...:....|..:|...|.||||..:|..:.|.:||:....:.|.:.:.|......:::
 Worm   214 -WRLASYLCAALSATVLPMIWYLPESPVFLEQKKKYKRAERSREKIAGICQLEYEPKAREEM--- 274

  Fly   339 NRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHVLVYYGLSLNVV-LLDGDKYNNFAYIALV 402
                  |..:...||: ..|:...|.....|||   :..|.|:|:.:. |..||...|| |:
 Worm   275 ------QDLKKITPIK-LLKSPVLRTNFLVLCW---MWFYVGMSVYITDLNSGDMAENF-YV--- 325

  Fly   403 EIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVL------------QLVLFLVG 455
               |.|              ||||:|.     :..|..|..:|.:            |::..|..
 Worm   326 ---GQF--------------LCGLVLT-----VSKIMIGILEPKIPWLGRRCLFISSQIIAILAY 368

  Fly   456 KLTITAS---------FQVLYFFA---------------SEIYPTNLRNSLLSFCSMMGRFGSML 496
            ...:||.         :.|.|..|               :|:.||::|....:..:::.:.|::|
 Worm   369 ITILTALWTRNKVSWWYTVAYILAYAGQSLCLETCYLSLAELMPTDVRTISGALMNILMKIGTIL 433

  Fly   497 APQTPLLAKYYANAPAMLFAGAAIVSGLLTL---FFPETTNVVLPTTVQ-------EADAIGVKK 551
            |..|..:..:|  .|.:......|.:|.|.:   :.||:.|:.:....|       :.|:...:|
 Worm   434 ASTTKPIKFWY--EPLLFIINTIICTGGLIIVWKYLPESKNMNMQLVGQDDIDEDEDDDSNKTEK 496

  Fly   552 QSK--SKDLDLVVTATQA 567
            .|:  |:....|.|:|:|
 Worm   497 PSEIPSEATKSVKTSTEA 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	122/565 (22%)
		MFS	146..530	CDD:119392	96/440 (22%)
Y57G11C.23	NP_502801.2	2A0119	<107..473	CDD:273328	95/425 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910