Protein Alignment SLC22A and F32H5.4

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001370023.1
• Gene: F32H5.4 / 185216
• WormBaseID: WBGene00009350
• Length: 528
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 138/566 - (24%)
• Similarity: 236/566 - (41%)
• Gaps: 87/566 - (15%)

  Fly     4 SEAPPADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAAT 68
            |..|..:..|::.||   .|:.|||..:| ||::           |..::|   ||...:.:.|
 Worm     8 SFGPNQENEVQLLPP---KEEKTLDNFMK-LGKY-----------CWLILF---FSEFMLLSGA- 53

  Fly    69 VTHRCSVEECDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEA 133
                         |:..|..:.. :.||    |.||      |.|. ....|||.:.....|...
 Worm    54 -------------GNTLYMMYAG-AYPK----LVSC------EGPD-VFIKDICKSSFDFHNPPN 93

  Fly   134 CAHNEFVFRDDEVTISNDFGIFC-DDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGG 197
            |.   ...:.|..:|:.|:|.|| :..|..:.: ::..:|...|....|.|||||||...:::..
 Worm    94 CT---ITSKYDFYSINVDYGHFCGEGAWVKTSI-SVQMVGVLIGSVTSGAVADRYGRLKVLSVCF 154

  Fly   198 ILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGE 262
            .:.:.|.::.:|:....:|.:...:.::....|.||..|..:|.|..:.|....::|:  :|...
 Worm   155 FMVSSLSILNTFAKDLIYFTIIRTILSIFKGGLLSTYGVYKMEHVPRQHRFWIATMIS--WAPNY 217

  Fly   263 VLLAMSAKAFHDWRILLRITYGPSLILLA-----YFWILPESVRWLLSQGKEERAKNILRRAAHV 322
            ::|:..|...|||     |||..::..|:     .|..:.||.|||:..|:.|.|:.:|:....|
 Worm   218 MILSFVAYLCHDW-----ITYQYAIFALSMPGAVVFLFVKESPRWLIQAGRIEEARQVLKHIMEV 277

  Fly   323 --NKRELPESVLDKLVLANRDKLQQSSESR--FPIREAFKNFKWRIANCSLCWI---VHVLVYYG 380
              |..:...:.:::::...:.:.::..:.|  :..|..|.| |:..:...:.|:   ......||
 Worm   278 DGNTSDHSWNEIEEMLQTEKKRQEERIKKRKNYDFRHLFWN-KYMASVTMILWLGMFSTSFTNYG 341

  Fly   381 LSLNVVLLDGDKYNNFAYI-ALVEIPGFFMPL--LIMDRFGRRYSLCGLMLASGL---CCIGTIF 439
            ...|:..|.|..|.|...: :|..:...|..|  |...:.||::    :.|.|.|   .|:.:||
 Worm   342 FVFNIEKLSGSLYINALLMGSLRWVLNIFFGLADLKFAKLGRKH----IHLISKLTITICVFSIF 402

  Fly   440 T------GADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAP 498
            .      ..|..::..|..|:...|.:..|........|.|||.:|||.:||.|...|.|::|.|
 Worm   403 VTYYFEYEEDYSLIIRVATLLASATASQVFITKSMVLMEFYPTVIRNSAVSFKSSASRIGTILGP 467

  Fly   499 QTPLLAKYYANAPAMLFAGAAIVSGL-LTLFFPETTNVVLPTTVQE 543
            |..:|.. |.:.|..:..|..:...: ..|..|||....||.|:.|
 Worm   468 QLFILCP-YKSLPYAILTGFCLFDAIAFQLRLPETKGKPLPETMPE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	100/419 (24%)
F32H5.4	NP_001370023.1	2A0119	<104..509	CDD:273328	104/418 (25%)