Protein Alignment SLC22A and C44C10.3

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_509958.2
• Gene: C44C10.3 / 183452
• WormBaseID: WBGene00008084
• Length: 474
• Species: Caenorhabditis elegans
• Alignment Length: 481
• Identity: 114/481 - (23%)
• Similarity: 183/481 - (38%)
• Gaps: 116/481 - (24%)

  Fly   112 LPQWNHSVDICSADHFTKN---KEACAHNEFVFRDDEVT-ISNDFGIFCDDEWKL-SMVGTINNL 171
            :|:|.     |.....||:   .::|..:...|.|...| ::.||...|...... |....:..|
 Worm    35 VPKWK-----CGDGPVTKDCKVYQSCPKDNLTFVDPIFTSVAMDFDWVCGSSAHYQSFFSLVQYL 94

  Fly   172 GQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVI----RSFSPSYGWFLVFEFLDNMTSSTLYS 232
            |...|..:.|.::|:|||...    |||..|:.:|    ...||:              ...|:.
 Worm    95 GVLVGTVLFGTLSDKYGRKPI----GILVIVIAIISLLGTGLSPN--------------RQLLFI 141

  Fly   233 TCFVIGIELVGPKRRVLAC--------------SVITVFYAVG--EVLLAMSAKAFHDWRILLRI 281
            ..|..|:.:.|    ||.|              .||..|:..|  .|.:.:......:||:...:
 Worm   142 ARFCSGLSIAG----VLVCICAWILESILSHQRMVIRAFFNWGWTRVFITVVCYLTQEWRLASYV 202

  Fly   282 TYG---PSLILLAYFWILPESVRWLLSQGKEERAKNI-----LRRAAHVNKRELPESVLDKLVLA 338
            ...   |:|::|.:  ::|||..||.|:|  |.||.|     :.:.|.|:...:...::....|.
 Worm   203 CAACLVPALLMLIF--LIPESAIWLHSKG--ETAKMIESEKFMAKIAGVSYVPIEHKLIHSKTLL 263

  Fly   339 NRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVE 403
            .....:...:..|.:        |      :.|....:..:...||...|.|:.|.|.|...::.
 Worm   264 ETLNTKGLFKKLFVL--------W------IMWFFVAVCGFANDLNSNSLAGNLYLNQALFGILL 314

  Fly   404 IPGFFMPLLI---MDRFGRRY----SLCGLMLASGLCCI-------GTIFTGADQPVLQLVLFLV 454
            :....:.|.:   .:.|.||.    |..|::::..:..|       ||.|         |:::|.
 Worm   315 VLSKIVLLFVDTKFENFKRRTLHQGSQSGMIISFLILAIFLWIDYHGTGF---------LIVYLF 370

  Fly   455 GKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANA---PAMLFA 516
            |.:.|..::..:|..|.|...|:.|.|.:..||:|.|.||:|||...     |||.   ||:.|
 Worm   371 GTMFIEYTWDAVYLCAIESMETSSRASAVGSCSLMARIGSLLAPFLT-----YANTWWPPAVYF- 429

  Fly   517 GAAIVSGLLTL-----FFPETTNVVL 537
             ..||.|.:.|     |..||.||.|
 Worm   430 -TIIVLGTVNLIISFMFLQETKNVNL 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	114/481 (24%)
		MFS	146..530	CDD:119392	101/435 (23%)
C44C10.3	NP_509958.2	2A0119	<64..456	CDD:273328	107/447 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910