Protein Alignment SLC22A and K09E9.1

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001368581.1
• Gene: K09E9.1 / 181654
• WormBaseID: WBGene00010724
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 458
• Identity: 102/458 - (22%)
• Similarity: 207/458 - (45%)
• Gaps: 69/458 - (15%)

  Fly   113 PQWNHSVDICSADHFTKNK-EACAHNEFVFRDDEVTISNDFGIFC--DDEWKLSMVGTINNLGQF 174
            |:|      |.....|:.. :...:|||      .::|.:.|..|  :.....:|:.::...|..
 Worm    85 PEW------CDTVRETEQSWKLNPNNEF------YSLSVERGFACQKNSNQTTAMMSSLLMWGAL 137

  Fly   175 FGIPIGGFVADRYGRSFSIALGGILGAVLG-VIRSFSPSYGWFLVFEFLDNMTSSTLYSTC---- 234
            .|..:.||::||.||. .:.||.:|...:| ::.:||....|..:     |.|.:.:...|
 Worm   138 IGSFVCGFLSDRLGRK-PVYLGCLLMITIGHILLTFSMYLSWMTI-----NATLAAMGFFCGGYM 196

  Fly   235 ---FVI---GIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDW----RILLRITYGPSLIL 289
               |||   ..||  ||.|:|..|:..  ::|...:.|::|....:|    .|...:....::|.
 Worm   197 VTNFVILTEAFEL--PKSRLLVVSLNG--WSVSMAVTALAASYTLNWYAYHTIFAIVGACIAIIS 257

  Fly   290 LAYFWILPESVRWLLSQGKEERAKNI-LRRAAHVNKRELPESVLDKLVLANRDKLQQS----SES 349
            ||   ...||.|||.:.|.:..||.| |:.....|.|::.|.  |..:|:..:.|..|    ::.
 Worm   258 LA---TCSESCRWLSANGLQNDAKKIALQITLLNNNRDIEED--DISILSWHEILGFSAPTHTDE 317

  Fly   350 RFPIREAFKNFKWRIANCSLCW--IVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLL 412
            :...:..||:.::......:|:  :...:|.:|...::.:|.|::|.|...:.:::....|.| .
 Worm   318 KKTWKTLFKSTRFLKPTAVMCYSFMASSIVSFGFYFSIDVLPGNRYYNMTIMGILKFILGFTP-F 381

  Fly   413 IMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPV----LQLVLFLVGKLT------ITASFQVLY 467
            .::||..:.::.  :.:.||||:..:..   .|:    :|.:.:::..|:      |..::::.:
 Worm   382 FLNRFLTKRAIA--ISSVGLCCLAALMI---LPIQYYDIQCMRWVIIMLSLMIAAGIDPTWKINH 441

  Fly   468 FFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVS-GLLTLFFPE 531
            .:::|::||::|:.....|:..||.||::||....|..:....|..:||....:. .::.:|.|:
 Worm   442 LYSAELFPTSVRSMARGVCNAGGRLGSVMAPMIVYLRTFGFFIPNAIFAVLLFIQLVVIVIFLPD 506

  Fly   532 TTN 534
            .::
 Worm   507 DSD 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	102/458 (22%)
		MFS	146..530	CDD:119392	94/418 (22%)
K09E9.1	NP_001368581.1	MFS	98..505	CDD:421695	97/433 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010