Protein Alignment SLC22A and pes-23

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_509167.2
• Gene: pes-23 / 180963
• WormBaseID: WBGene00003987
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 456
• Identity: 107/456 - (23%)
• Similarity: 186/456 - (40%)
• Gaps: 94/456 - (20%)

  Fly   123 SADHFTKNKEACAHNEFVFRDDEVTISNDFGIFCDDEWKLSM-----VGTINNLGQFFGIPIGGF 182
            |.|.:.:..|..:.|:|....:.....:....:..|:..:|:     |..|..:|.|.|..:.|:
 Worm    37 STDDYLQQAERVSKNDFYRFINNSNFYSTHAQWITDDTNVSVLWWENVIAIQQVGIFVGSILFGY 101

  Fly   183 VADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTC-FVIG-------- 238
            ::|.:||........::.:|:.::..|               ::|:.|.:.| |:||
 Worm   102 ISDHFGRQKVCQYSLLISSVILLVEGF---------------LSSTILIALCRFIIGTQTGAIIV 151

  Fly   239 ------IELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSLI-LLAYFWIL 296
                  .||:.|:.|.||.:...  :..|:..||:......:|||.|.:....:|. .|.|.:.:
 Worm   152 VSWSLTTELISPRTRFLARAFAN--WPTGKFALALICFFSQNWRISLHVCAAFTLFGALLYIFFV 214

  Fly   297 PESVRWLLSQGKEERAKNILRRAAHVNKRE-------LPESVLDKLVLANRDKLQQSSESRFPI- 353
            |||..:|...||...|.||:   |.|.|..       ||..:..|                 |:
 Worm   215 PESPTYLQCHGKRTEAHNIV---ADVFKNSNGKCVIALPGGIRSK-----------------PLT 259

  Fly   354 -REAFKNFKWR--IANCSLCWIV-----------HVLVYY-GLSLNVVLLDGDKYNNFAYIALVE 403
             |:.:|..|:|  |......|::           .|:::: .|.|:.:||.|........:.|||
 Worm   260 FRQIWKKEKYRNVIILFGSIWVMTNFTATMLDFSEVIIFHNNLILSQMLLAGVPAICKILLGLVE 324

  Fly   404 IPGFFMPLLIMDRFGRRYSLC--GL-MLASGLCCIGTIFTGADQ--PVLQLVLFLVGKLTITASF 463
            |  :|.  :|..|.....|||  |: |.|||:    .|..|..:  |.:.:::||:|..:|...:
 Worm   325 I--YFG--IISRRNLHLISLCINGISMCASGV----LILFGLQKNYPTIYVLVFLIGYASIEFIW 381

  Fly   464 QVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLF 528
            ...|....|..||.:|.::...||.:.|...:||.:..::.:.:..||..:....||:..|:..|
 Worm   382 DACYLCVVEQVPTEVRGTISGACSFLSRLSGILASKMTIVKQRWEPAPLFIAFATAIIHFLIAFF 446

  Fly   529 F 529
            |
 Worm   447 F 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	104/443 (23%)
pes-23	NP_509167.2	2A0119	<82..458	CDD:273328	100/411 (24%)