Protein Alignment SLC22A and Y51A2D.18

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_507620.2
• Gene: Y51A2D.18 / 180202
• WormBaseID: WBGene00013083
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 577
• Identity: 126/577 - (21%)
• Similarity: 221/577 - (38%)
• Gaps: 156/577 - (27%)

  Fly    20 KDSEDV-TLDAILKHLGQFGRFQLIIFL---LICLPMMFHAMFSVTYVFTAATVTHRCSVEECDL 80
            |:.|.| .||..:    |.|::.|::.|   |:.||.: .:||.:.|...|..|.
 Worm    27 KEPEQVHGLDDYI----QMGKYVLLVCLAAELLILPQV-SSMFYMMYAGAAPRVI---------- 76

  Fly    81 PGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEA-CAHNEFVFRDD 144
                                  ||:......|.:   ..:||    |..:|.. |:|.||.::..
 Worm    77 ----------------------SCDNIVFDSLLE---GKEIC----FELDKMGNCSHPEFQYQFR 112

  Fly   145 EVTISNDFGIFCDDEWKLSMVGTINNLG-QFFGIPIG----GFVADRYGRSFSIALGGILGAVLG 204
            .:.:  ::..||:.. ||    ..|::. |.||:..|    |.::|.:||..     |...|.||
 Worm   113 SINV--EYNYFCNTS-KL----VKNSISVQMFGVLTGSIVFGQISDSFGRKI-----GSQVASLG 165

  Fly   205 VIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSA 269
            ::      .||.:|.: ..|:...|:..|  ::|....|      :.|:|.||      ::....
 Worm   166 ML------IGWLIVVQ-SRNLLHFTISRT--IVGFFTGG------SISIINVF------IMENIP 209

  Fly   270 KAFHDWRILLRITYGPSLILLAYF-WI-------------------------LPESVRWLLSQGK 308
            |....| |.:.||:.|::.:.:|| |:                         :.||.|||:::||
 Worm   210 KKHRMW-INMAITWSPNMPIYSYFAWLASDWKSLAYINAFMCIPGILFFQFFIHESPRWLVTRGK 273

  Fly   309 EERAKNILRRAAHVNKRE--LPESVLDKLVLA-NRDKLQQSSESRFPIREAFKNFKWRIANCSLC 370
            ...|..:|:|....:.:|  :.|...:.|.:. .:.:.|.:.:::|.....|...|..|....|.
 Worm   274 ISEAVQVLQRQLKTSNQENLIHEDFEENLRMEYAKTQAQNTRKTKFSYYHLFVTPKLAITTIVLA 338

  Fly   371 --WIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIP---GFFMPLLIMDRFGRRYSLCGLMLAS 430
              :....::.||:..|:..|.|..|.|..|..|:...   .|....|.....||::     :..|
 Worm   339 YSYCATSIINYGVLFNMEKLSGSIYWNSVYTGLMRYACNLSFGYADLKFKSIGRKF-----IHTS 398

  Fly   431 GLCCIG---TIFTGA--------DQPVLQLVLFLVGKLTITASFQVLY----FFASEIYPTNLRN 480
            ||..|.   ::..|:        .:.|:::.:.|...:|     ..:|    ..::|::||.:|.
 Worm   399 GLVIIVLSLSLVVGSYALHLNHEMKDVIRISILLASSMT-----SQIYIADGIVSAELFPTPIRT 458

  Fly   481 SLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGLLTLF-----FPET 532
            ...:|..:..|.|.:|:|....||.|:...|....    |:..|:..|     .|||
 Worm   459 IGYAFLQLWNRVGVVLSPFIFYLADYWLALPFCFM----ILFSLIDTFSFECLLPET 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	121/561 (22%)
		MFS	146..530	CDD:119392	95/442 (21%)
Y51A2D.18	NP_507620.2	2A0119	24..519	CDD:273328	126/577 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010