Protein Alignment SLC22A and K11D9.3

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_499382.1
• Gene: K11D9.3 / 176510
• WormBaseID: WBGene00010772
• Length: 480
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 123/555 - (22%)
• Similarity: 221/555 - (39%)
• Gaps: 127/555 - (22%)

  Fly    46 LLICLPMMFHAMFSVTYVFTAATVTHRCSVEECDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNS 110
            ||:.|...|...|:...:|                |..:.|.|  .|:. .||:....|:.|
 Worm    10 LLVLLTWQFSIFFASQQIF----------------PIFSNYVP--QWTC-GNGEPTSDCSVY--- 52

  Fly   111 ELPQWNHSVDICSADHFTKNKEACAHN-EFV---FRDDEVTISNDFGIFCDDEWKLSMVGTINNL 171
                                 |:|..| .||   |:    :.:.::...|.   |.:.:.::.:.
 Worm    53 ---------------------ESCKSNLTFVNVAFK----SAAMEYDWICG---KSAYLKSLFSQ 89

  Fly   172 GQFFGIPIG----GFVADRYGRS----FSIALGGILGAVLGVIRSFSPSYGWFL-VFEFLDNMTS 227
            .||.|:..|    |.|:|..||.    |:::||.::..|.|:    :|:|...| :..||.....
 Worm    90 IQFAGVLCGTFSFGAVSDVVGRKPVAVFALSLGILMNFVTGL----APNYQVLLGIRFFLGLSVG 150

  Fly   228 STLYSTCFVIGIELVGPKRRVLACSVITVFY--AVGEVLLAMSAKAFHDWR---ILLRITYGPSL 287
            .||...|..: :|::.|::|:    .:..|:  .|..:::.:.|.|..:||   |...:...|:|
 Worm   151 GTLVVVCTFV-MEMLLPQQRM----ALRAFFNWGVARLMMTLIAMALPEWRMSSIACAVAALPAL 210

  Fly   288 ILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRE-LPESVLDKLVLANRDKLQQSSESRF 351
            |::.:  :.|||..||.::|:.:..|   :...|:.|.. :|...::...:.:...:.:..:::.
 Worm   211 IIIVF--VFPESPTWLHNKGRLDEMK---KSEKHIAKMAGVPYVPIEHKRIEHSKTVMEMLQTKG 270

  Fly   352 PIREAFKNFKWRIANCSLCWIVHVLVYYGLSLNVVLLDGDKY-NNFAYIALVEIPGFFMPLLIMD 415
            .:...|  ..|.:      |.|..:..|...||...:.||.: |...:..|:.:..  |.|::.|
 Worm   271 LMSRLF--VLWSM------WFVASICGYATDLNSNTISGDLFVNQILFSILIAVSK--MILVVFD 325

  Fly   416 ----RFGRRYSLCGLMLASGLCCIGTIF------TGADQPVLQLVLFLVGKLTITASFQVLYFFA 470
                .|.||....|..|...:|.:...|      ||    :..|::.|:|.:.|..::...|..|
 Worm   326 THVPSFRRRTLHQGAQLVVCICFLILTFMTFNGYTG----LAFLIVNLIGTVFIEYTWDACYLCA 386

  Fly   471 SEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANA--PAMLFAGAAIVSGLLTL-----F 528
            .|...|..|.|....||::.|.|::|||..     .|||.  |..::. ..::.|.:.|     |
 Worm   387 VESMETACRASATGTCSLVARIGAILAPML-----NYANLWWPPSVYL-TVVLLGTINLIISYFF 445

  Fly   529 FPETTNVVL------PTTVQEADAIGVKKQSKSKD 557
            ..||.||.|      |::.:....|..|...|:.:
 Worm   446 LVETKNVNLDNVHIDPSSEEGTPMIDEKPAQKTSE 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	98/430 (23%)
K11D9.3	NP_499382.1	2A0119	<66..454	CDD:273328	99/428 (23%)