Protein Alignment SLC22A and svop-1

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_498960.2
• Gene: svop-1 / 176250
• WormBaseID: WBGene00014021
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 133/542 - (24%)
• Similarity: 213/542 - (39%)
• Gaps: 129/542 - (23%)

  Fly    80 LPGSNYYEPHTNWSIPKNGKDL-----DSCNRYTN-SELPQWNHSVDICSADHFTKNKEACAHNE 138
            |..||..|.:.:.:..:..|::     |...||:| .:..:.....|..|.|           :|
 Worm    11 LEASNLTEAYVDLTAKQLIKEIRHVGDDFAVRYSNLDDRTELGEPTDQRSPD-----------SE 64

  Fly   139 FVFRDDEVTISNDFGIF------------------------------CDDEWKLS-----MVGTI 168
            ..|..||...:..||.|                              |  ||.:|     :|.|.
 Worm    65 KTFTVDEAVEALGFGRFQLKLSILTGMAWMADAMEMMLLSLISPALAC--EWGISSVQQALVTTC 127

  Fly   169 NNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNM------TS 227
            ...|........|.:.||:||...:....::..::|||...||.:...|.|..|...      .|
 Worm   128 VFSGMMLSSTFWGKICDRFGRRKGLTFSTLVACIMGVISGMSPHFYVLLFFRGLTGFGIGGVPQS 192

  Fly   228 STLYSTCFVIGIELVGPKRRVLACSVITVFYAVG---EVLLAMSAKAFHDWRILLRITYGP-SLI 288
            .|||:       |.:...:|.....:|..|:|:|   |.|||........||.|:.::..| .:.
 Worm   193 VTLYA-------EFLPTAQRAKCVVLIESFWAIGAVFEALLAYFVMESFGWRALMFLSSLPLGIF 250

  Fly   289 LLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQQSSESRFPI 353
            .:|.|| ||||.|:.::.|..|||...|:.||.:|:.:||..   :||.:.:    ..||||..|
 Worm   251 AVASFW-LPESARFDMASGHPERALETLQAAARMNRVQLPTG---RLVSSTK----AGSESRGDI 307

  Fly   354 REAFKN-------FKWRIANCSLCWIVHVLVYYGLSLNVVLL-------DGDKYNNFAYI----- 399
            ......       ..|.|      |.:....|||:.|...:|       .|..::|...:
 Worm   308 ANLLSPDLRKTTILLWCI------WAITAFSYYGMVLFTTVLFQSHDECHGGLFSNGTQMEVCQP 366

  Fly   400 ------------ALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGT--IFTGADQPVLQLV 450
                        .|.|.||..:.:||::.|||:.::.   |...:..|.|  ::...|:..:.::
 Worm   367 LTRSDYFDLLSTTLAEFPGLIITVLIIEWFGRKKTMA---LEYAVFAIFTFLLYFCLDRFTVTVL 428

  Fly   451 LFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYA----NAP 511
            :| |.:..|:.:||..|.:..|:|||.||...|..||.|.|.|:::   ||.:|:..:    :.|
 Worm   429 IF-VARAFISGAFQCAYVYTPEVYPTTLRAVGLGTCSAMARIGAIV---TPFIAQVASEKSLSLP 489

  Fly   512 AMLFAGAAIVSGLLTLFFPETT 533
            ..::..|||:..:.:|..|..|
 Worm   490 IGIYGTAAILGLIASLSLPIET 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	133/542 (25%)
		MFS	146..530	CDD:119392	115/465 (25%)
svop-1	NP_498960.2	2A0119	16..514	CDD:273328	130/537 (24%)
		MFS	87..508	CDD:119392	112/450 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.666667	Normalized mean entropy	S2472
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860