Protein Alignment SLC22A and ZK892.3

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_496162.1
• Gene: ZK892.3 / 174558
• WormBaseID: WBGene00014127
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 123/566 - (21%)
• Similarity: 211/566 - (37%)
• Gaps: 124/566 - (21%)

  Fly    38 GRFQLIIFLLICLPMMFHAMFSVTYVF---------TAATVTHRC-SVEECDLPGSNYYEPHTNW 92
            |:::|.: :::||..| ...||...||         ||.|..:.| .:|...|  |:|.|...|.
 Worm     6 GQWRLDV-MMMCLYQM-ALFFSAQLVFVIFLEYMPKTACTEKNYCYKLESKCL--SDYDENKPNI 66

  Fly    93 SIPKNG--KDLDSC---NRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFVFRDDEVTISNDF 152
            .:..||  ...|.|   .:|...|..|..:..|..|..|::
 Worm    67 CLVPNGSKSQFDECVNDKKYLYFESAQHYYQQDCTSLTHYS------------------------ 107

  Fly   153 GIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRS----FSIALGGILGAVLGVIRSFS-PS 212
                        ..|...||..|...|.|.:||:.||.    .|||:|     |:.:|.|.: ||
 Worm   108 ------------ASTNMYLGVLFANLILGVLADKLGRRPIFFASIAIG-----VVSLILSAAIPS 155

  Fly   213 YGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVF--YAVGEVLLAMSAKAFHDW 275
            ...|.:|.|...:..:......:..|.|::..|||.    .:..|  :|...:|:...|.....|
 Worm   156 LIAFYIFRFTTGVGVAGAQIVGWSYGSEMISAKRRF----QLRTFSNWANARILVVFVAFITRRW 216

  Fly   276 RILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKLVLANR 340
            .....:....|.::....|.||||..:|..:.:.|.|.....:.|.:...|..|.  :...:.|.
 Worm   217 DTASYVCAAISALIFPILWKLPESPVFLEQKHRIEEANEAREQLAELCDMEYEEK--EAAAINNL 279

  Fly   341 DKLQQSSESRFPIREAFKNFKWRIANCSLC--WIVHVLVYYGLSLNVVLLDGDKYNNFAYIA--- 400
            .|:        ...:.::|.:.|.....||  |.     :.|::..:..|:|...:...|:.
 Worm   280 KKI--------TFMDLWRNERLRTNFLVLCFMWF-----FVGMATYITDLNGADMSTNLYVGQFL 331

  Fly   401 ---LVEIP----GFFMPLLIMDRF---GRRYSLC---GLMLASGLCCIGTIFTGADQPVLQLVLF 452
               |:.|.    ||..|     ||   |||....   |:.:.:.:..:..:.|...:....|:::
 Worm   332 SGLLLTISKIIFGFAEP-----RFEWLGRRAIFLFSQGVAIIAYILILVALVTSNKETTWYLIVY 391

  Fly   453 LVGKLTITASFQVL-----YFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPA 512
            |     ...|||.|     |...:|:.||::|.::.:..::..|.|:::|..|..|.  ::..|.
 Worm   392 L-----CAYSFQALATETCYLSVAELIPTDVRVTVAAITNICLRLGTIVASLTKPLK--FSFEPG 449

  Fly   513 MLFAGAAIVS-GLLTLFF--PETTNVVLPTTVQEADAIGVKKQSKS 555
            :......:.| |:..::|  .|:.||.|....|:.:.....:.||:
 Worm   450 LFLINLIVCSIGITVVYFYLEESRNVNLQHVGQDEEPSAEDEHSKA 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	120/549 (22%)
		MFS	146..530	CDD:119392	87/416 (21%)
ZK892.3	NP_496162.1	2A0119	<108..477	CDD:273328	90/404 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840