Protein Alignment SLC22A and B0252.3

DIOPT Version :10

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001021888.1
• Gene: B0252.3 / 174130
• WormBaseID: WBGene00015088
• Length: 484
• Species: Caenorhabditis elegans
• Alignment Length: 434
• Identity: 128/434 - (29%)
• Similarity: 206/434 - (47%)
• Gaps: 29/434 - (6%)

  Fly   132 EACAHNEFVFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALG 196
            :|..::.|:...||..::.|.....:......|||  |.:|..|..|:    ||.|||.......
 Worm    69 KASENSSFIGVADEFDLTGDASWLAESTTTFYMVG--NMIGGMFIPPL----ADHYGRLPVFVAT 127

  Fly   197 GILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVG 261
            .:|.||.|:|.:||.|...|.:...:..:..:......:|:|.|....:.|........|.:.||
 Worm   128 VLLMAVGGMISAFSTSIMMFCIMRMIHGIFYTAAGLAGWVLGYENTPLRLRFFTSVYFGVMWVVG 192

  Fly   262 EVLLAMSAKAFHDWRILLRITYGPSL-ILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKR 325
            ...|.:.|....|||.|:.....|:: :.|..:..:|||:.:|:|..:.|:.:      |.:.|.
 Worm   193 ACFLGLLAYILPDWRYLMFCISVPNIFVALLIYMTVPESLHFLVSSQQNEKIE------AWLEKI 251

  Fly   326 ELPE---SVLDKLVLANRDKLQQSSESRFPIREAFKN--FKWRIANCSLCWIVHVLVYYGLSLNV 385
            ..|:   |..|  ::.:||  :..|..:...||.:|:  |...:...:..|||...:|:||:...
 Worm   252 RGPKGDISASD--IVEDRD--ENGSSFKTLCREMWKHKMFIVYVLVMTYIWIVDTFIYFGLAFYS 312

  Fly   386 VLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVLQLV 450
            ..|.|:.|.||..::|||.|.:....:.|:::||:..:.|..:.:||..:|.:.:   .....:.
 Worm   313 TNLAGNLYLNFVLMSLVEAPAYIFSPIFMNKYGRKVLISGTHIIAGLSFLGIVLS---SEAWHIH 374

  Fly   451 LFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLF 515
            .:|:||..|:.||..:|.|||||:||:.||..:.||..:.|||.||:|....|...:|.|||:..
 Worm   375 FWLLGKFAISCSFMSIYMFASEIFPTDGRNKCIGFCETLSRFGGMLSPYLSHLTAVHALAPAITL 439

  Fly   516 AGAAIVSGLLTLFFPETTNVVLPTTVQEA----DAIGVKKQSKS 555
            :..|:..|||||..|||.|..||:|:.|.    ..|..|..|.|
 Worm   440 SLIAVSGGLLTLILPETLNTKLPSTIAETASRRQLIDDKSDSSS 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	115/399 (29%)
B0252.3	NP_001021888.1	MFS_SLC22	73..454	CDD:340875	115/399 (29%)