Protein Alignment SLC22A and K05F1.6

DIOPT Version :9

• Sequence 1: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001342018.1
• Gene: K05F1.6 / 173977
• WormBaseID: WBGene00019408
• Length: 858
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 163/643 - (25%)
• Similarity: 264/643 - (41%)
• Gaps: 133/643 - (20%)

  Fly     5 EAPPADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATV 69
            |..|.||             :..:.||..:|....:|:.|::||.|..:.||||::..|:.....
 Worm   193 EGKPTDP-------------IDFEGILNIIGGCRWWQIWIYVLIALQQIPHAMFNLNVVYMMYDP 244

  Fly    70 THRCSVEECDLPGSNYYEPHTN-----------WSI----------PKNGKD----LDSCNRYTN 109
            ..:|.|     ||.|    .||           |.:          |....|    .|||..|..
 Worm   245 EFQCMV-----PGFN----DTNDTTISSHGPYLWGVDDIKNISFVFPNANSDGAYQRDSCYFYER 300

  Fly   110 SE--------LP-------QWNHSVDI-----CSADHFTKNKEACAHNEFVFRDDEVTISNDFGI 154
            ||        :|       .|.   |:     |.|.||.|:...            .||..||.:
 Worm   301 SEERYRQLRRMPLETAMSEAWK---DVAPKKKCQAYHFEKDVMV------------ETIVTDFNL 350

  Fly   155 FCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVF 219
            .||..:.........::|...|..:||..:|:.||..:|...|||.::|||...|:..|..||:.
 Worm   351 VCDSWFAKGHAHMFYSIGYLLGCVLGGIASDKIGRKPTIIGFGILSSMLGVFLPFNDYYPMFLLI 415

  Fly   220 EFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRITYG 284
            ..|..:.:.......:.:.:|:.|.|.|.:..|::...:|:|..|||:.|.....|:.:..|..|
 Worm   416 RLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAG 480

  Fly   285 PSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRE---------------LPESVLDK 334
            ...:.:.:...:|||.|||:.|.:...|:.::|:|.    ||               ||..:  :
 Worm   481 LHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKAC----REPPFPFNMCTTSKCGNLPSDL--E 539

  Fly   335 LVLANRDKLQQSSESRFPIREAF--KNFKWRIANCSLCWIVHVLVYYGLSLNV--------VLLD 389
            ||.....||.:.:..:....:.|  |..::|..:..:.::...||||||.:.:        .|..
 Worm   540 LVSHRERKLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFT 604

  Fly   390 GDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFT-GADQPVLQLVLFL 453
            |..:.|......:|||..|..:.:| :.||:.:|...::.|||..|..:.: .:...:|.|....
 Worm   605 GYFHLNNGIAGAIEIPTLFACVWMM-QLGRKKALMLTLITSGLFIIVAMLSMVSGHYMLALAFMY 668

  Fly   454 VGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKY-YANAPAMLFAG 517
            .||:.:..:|.:||.|.||:|||.:||:.:...||:.||||.|:....||:.. ....|.::||.
 Worm   669 FGKIAVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLSNISLPIVPMIIFAV 733

  Fly   518 AAIVSGLLTLFFPETTNVVLPTTVQEA-----------------DAIGVKKQSKSKDL 558
            .::.:|:|....|||:...||.|:.:|                 ...|.:|.:||..|
 Worm   734 FSLFAGMLVFVLPETSEKPLPETLDDAINFLEPTKQVNCMMGRFGVFGHQKMTKSISL 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	150/576 (26%)
		MFS	146..530	CDD:119392	110/410 (27%)
K05F1.6	NP_001342018.1	MFS_SLC22	333..746	CDD:340875	113/431 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163100
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850